R
Reda A. Abdelhamid
Researcher at Al-Azhar University
Publications - 15
Citations - 100
Reda A. Abdelhamid is an academic researcher from Al-Azhar University. The author has contributed to research in topics: Docking (molecular) & Chemistry. The author has an hindex of 4, co-authored 15 publications receiving 36 citations. Previous affiliations of Reda A. Abdelhamid include Yamagata University & Al-Farabi University.
Papers
More filters
Journal ArticleDOI
Identification of Potential SARS-CoV-2 Main Protease and Spike Protein Inhibitors from the Genus Aloe : An In Silico Study for Drug Development.
Mohamed E. Abouelela,Hamdy K. Assaf,Reda A. Abdelhamid,Ehab S Elkhyat,Ahmed M. Sayed,Tomasz Oszako,Lassaad Belbahri,Ahmed E. El Zowalaty,Mohamed Salaheldin A. Abdelkader +8 more
TL;DR: In this article, the authors employed an in-silico approach involving molecular docking, dynamics simulation, and binding free energy calculation using SARS-CoV-2 essential proteins as main protease and spike protein to identify lead compounds from Aloe that may help in novel drug discovery.
Journal ArticleDOI
Bioactive constituents from Thunbergia erecta as potential anticholinesterase and anti-ageing agents: Experimental and in silico studies
Mohamed S. Refaey,Reda A. Abdelhamid,Hanan Elimam,Yaseen A.M.M. Elshaier,Ahmed Ali,Mohamed A.A. Orabi +5 more
TL;DR: In this paper, a phytochemical study of Thunbergia erecta aerial parts resulted in the isolation of ten compounds (1, 10) based on spectral data and comparison with literature values.
Journal ArticleDOI
Anti-Alzheimer's flavanolignans from Ceiba pentandra aerial parts
Mohamed E. Abouelela,Mohamed A.A. Orabi,Reda A. Abdelhamid,Mohamed Salaheldin A. Abdelkader,Faten M. Darwish,Mayumi Hotsumi,Hiroyuki Konno +6 more
TL;DR: Four flavanolignans, ceibapentains A and B and cinchonains Ia (3) and Ib (4), were isolated for the first time from an ethyl acetate extract of Ceiba pentandra aerial parts and showed anti-Alzheimer's activity via an assessment of their inhibitory effect on amyloid β42 aggregation.
Journal ArticleDOI
Ethyl acetate extract of Ceiba pentandra (L.) Gaertn. reduces methotrexate-induced renal damage in rats via antioxidant, anti-inflammatory, and antiapoptotic actions.
Mohamed E. Abouelela,Mohamed A.A. Orabi,Mohamed A.A. Orabi,Reda A. Abdelhamid,Mohamed Salaheldin A. Abdelkader,Hafez R. Madkor,Faten M. Darwish,Tsutomu Hatano,Bakheet E. M. Elsadek +8 more
TL;DR: Data demonstrate that C. pentandra exhibits nephroprotective effect against MTX-induced kidney damage via its antioxidant, antiapoptotic and anti-inflammatory mechanisms.
Journal Article
Chemical and Cytotoxic Investigation of Non-Polar Extract from Ceiba Pentandra (L.) Gaertn.: A Study Supported By Computer Based Screening -
Mohamed E. Abouelela,Mohamed A.A. Orabi,Reda A. Abdelhamid,Mohamed Salaheldin A. Abdelkader,Faten M. Darwish +4 more
TL;DR: In this paper, the authors reported on the gas chromatography profile of fatty acids, other related lipids and hydrocarbons of the non-polar methylene chloride fraction of the extract of the ornamental tree Ceiba pentandra (L.) Gaertn.