R
Rehan Akbani
Researcher at University of Texas MD Anderson Cancer Center
Publications - 134
Citations - 106557
Rehan Akbani is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 65, co-authored 124 publications receiving 84443 citations. Previous affiliations of Rehan Akbani include University of Texas at San Antonio & National Institutes of Health.
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Explore, visualize, and analyze functional cancer proteomic data using the cancer proteome atlas
TL;DR: A user-friendly, open-access bioinformatic resource, The Cancer Proteome Atlas (TCPA), which contains two separate web applications that provide various analytic and visualization modules to help cancer researchers explore these datasets and generate testable hypotheses in an effective and intuitive manner.
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Using reverse-phase protein arrays as pharmacodynamic assays for functional proteomics, biomarker discovery, and drug development in cancer.
Yiling Lu,Shiyun Ling,Apurva M. Hegde,Lauren Averett Byers,Kevin R. Coombes,Gordon B. Mills,Rehan Akbani +6 more
TL;DR: RPPA technology has emerged as a robust, sensitive, cost-effective approach to the analysis of large numbers of samples for quantitative assessment of key members of functional pathways that are affected by tumor-targeting therapeutics.
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TCPA v3.0: An Integrative Platform to Explore the Pan-Cancer Analysis of Functional Proteomic Data *
Mei-Ju May Chen,Jun Li,Yumeng Wang,Rehan Akbani,Yiling Lu,Gordon B. Mills,Gordon B. Mills,Han Liang +7 more
TL;DR: The value of this module is demonstrated by examining the correlations of RPPA proteins with significantly mutated genes, assessing the predictive power of somatic copy-number alterations, DNA methylation, and mRNA onprotein expression, inferring the regulatory effects of miRNAs on protein expression, constructing a co-expression network of proteins and pathways, and identifying clinically relevant protein markers.
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Focal adhesion kinase: an alternative focus for anti-angiogenesis therapy in ovarian cancer.
Rebecca L. Stone,Keith A. Baggerly,Guillermo N. Armaiz-Pena,Yu Kang,Angela Sanguino,Duangmani Thanapprapasr,Heather J. Dalton,Justin Bottsford-Miller,Behrouz Zand,Rehan Akbani,Lixia Diao,Alpa M. Nick,Koen DeGeest,Gabriel Lopez-Berestein,Robert L. Coleman,Susan K. Lutgendorf,Anil K. Sood +16 more
TL;DR: FAK may be a unique therapeutic target in EOC given the dual anti-angiogenic and anti-metastatic potential of FAK inhibitors.
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HEAP: A packet authentication scheme for mobile ad hoc networks
TL;DR: This work studies packet authentication in wireless networks and proposes a hop-by-hop, efficient authentication protocol, called HEAP, which authenticates packets at every hop by using a modified HMAC-based algorithm along with two keys and drops any packets that originate from outsiders.