R
Rehan Akbani
Researcher at University of Texas MD Anderson Cancer Center
Publications - 134
Citations - 106557
Rehan Akbani is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 65, co-authored 124 publications receiving 84443 citations. Previous affiliations of Rehan Akbani include University of Texas at San Antonio & National Institutes of Health.
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Interactive Clustered Heat Map Builder: An easy web-based tool for creating sophisticated clustered heat maps.
Michael C. Ryan,Mark Stucky,Chris Wakefield,James M. Melott,Rehan Akbani,John N. Weinstein,Bradley M. Broom +6 more
TL;DR: This web-based Interactive Heat Map Builder can be used by investigators with no bioinformatics experience to generate high-caliber, publication quality maps.
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A Comprehensive Comparison of Normalization Methods for Loading Control and Variance Stabilization of Reverse-Phase Protein Array Data
TL;DR: The invariant marker set method performs well with respect to LC, variance stabilization and association with the immunohistochemistry/florescence in situ hybridization data for three key markers in breast tumor samples, while the other methods have inferior performance.
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Molecular heterogeneity at the network level:high-dimensional testing, clustering and a TCGA case study
Nicolas Städler,Frank Dondelinger,Steven M. Hill,Rehan Akbani,Yiling Lu,Gordon B. Mills,Sach Mukherjee +6 more
TL;DR: Recent ideas from high‐dimensional statistics for testing and clustering in the network biology setting are leveraged and can be applied directly to most continuous molecular measurements and networks do not need to be specified beforehand.
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Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas
Jian Chen,Gottumukkala S. Raju,Wilma Jogunoori,Vipin Kumar Menon,Avijit Majumdar,Jiun Sheng Chen,Young Jin Gi,Yun Seong Jeong,Liem Phan,Mitchell Belkin,Shoujun Gu,Suchin Kundra,Nipun A. Mistry,Jianping Zhang,Xiaoping Su,Shulin Li,Sue Hwa Lin,Milind Javle,John S. McMurray,Thomas F. Rahlfs,Bibhuti Mishra,Jon White,Asif Rashid,Nicole Beauchemin,Brian Weston,Mehnaz A. Shafi,John R. Stroehlein,Marta L. Davila,Rehan Akbani,John N. Weinstein,Xifeng Wu,Lopa Mishra,Lopa Mishra,Lopa Mishra +33 more
TL;DR: This study uncovers diverse mutational processes underlying the transition from early adenoma to cancer, which has broad implications for biomarker-driven targeting of CEA/TGF-β in high-risk adenomas and may lead to early detection of aggressive adanoma to CRC progression.
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Personalized Integrated Network Modeling of the Cancer Proteome Atlas.
Min Jin Ha,Sayantan Banerjee,Rehan Akbani,Han Liang,Gordon B. Mills,Kim Anh Do,Veerabhadran Baladandayuthapani +6 more
TL;DR: In this article, a personalized cancer-specific integrated network estimation (PRECISE) model is proposed to identify patient-specific variations in signaling pathways and activities within and across tumors.