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Rehan Akbani
Researcher at University of Texas MD Anderson Cancer Center
Publications - 134
Citations - 106557
Rehan Akbani is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 65, co-authored 124 publications receiving 84443 citations. Previous affiliations of Rehan Akbani include University of Texas at San Antonio & National Institutes of Health.
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Large-scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines
Wei Zhao,Jun Li,Mei-Ju May Chen,Zhenlin Ju,Nicole K. Nesser,Katie Johnson-Camacho,Christopher Boniface,Yancey Lawrence,Nupur T. Pande,Michael A. Davies,Meenhard Herlyn,Taru A. Muranen,Ioannis K. Zervantonakis,Erika von Euw,Andre Schultz,Shwetha V. Kumar,Anil Korkut,Paul T. Spellman,Rehan Akbani,Dennis J. Slamon,Joe W. Gray,Joan S. Brugge,Yiling Lu,Gordon B. Mills,Han Liang +24 more
TL;DR: It is shown that integrating protein response signals substantially increases the predictive power for drug sensitivity and aids in gaining insights into mechanisms of drug resistance, and a systematic map of protein-drug connectivity is built and developed.
Proceedings ArticleDOI
A Machine Learning Based Reputation System for Defending Against Malicious Node Behavior
TL;DR: This paper delineated the factors associated with building the SVM based RS and then proposed and evaluated the technique, and showed that the RS significantly outperforms TrustGuard and correctly distinguishes between good and malicious nodes with high accuracy.
Journal ArticleDOI
Bayesian Hierarchical Varying-Sparsity Regression Models with Application to Cancer Proteogenomics
TL;DR: A novel regression framework, Bayesian hierarchical varying-sparsity regression (BEHAVIOR) models to select clinically relevant disease markers by integrating proteogenomic (proteomic+genomic) and clinical data and finds several interesting prognostic proteins and pathways that are shared across multiple cancers and some that exclusively pertain to specific cancers.
Proceedings ArticleDOI
Abstract 4262: A pan-cancer proteomic analysis of The Cancer Genome Atlas (TCGA) project
Rehan Akbani,Kwok-Shing Ng,Henrica M.J. Werner,Fan Zhang,Zhenlin Ju,Wenbin Liu,Ji Yeon Yang,Yiling Lu,John N. Weinstein,Gordon B. Mills +9 more
TL;DR: The findings demonstrate the power of pan-cancer proteomic analysis, identifying several novel single-tumor and cross-Tumor targets and pathways and supporting the ability of RPPA analysis to yield high-quality information from TCGA samples.
Proceedings ArticleDOI
HEAP: hop-by-hop efficient authentication protocol for Mobile Ad-hoc Networks
TL;DR: This work studies packet authentication in wireless networks and proposes a Hop-by-hop, Efficient Authentication Protocol, called HEAP, which authenticates packets at every hop by using a modified HMAC-based algorithm along with two keys and drops any packets that originate from outsiders.