R
Ren-Ke Li
Researcher at University Health Network
Publications - 184
Citations - 7881
Ren-Ke Li is an academic researcher from University Health Network. The author has contributed to research in topics: Transplantation & Heart failure. The author has an hindex of 50, co-authored 184 publications receiving 7070 citations. Previous affiliations of Ren-Ke Li include Shanxi Medical University & University of Toronto.
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Journal ArticleDOI
Flexible shape-memory scaffold for minimally invasive delivery of functional tissues.
Miles Montgomery,Samad Ahadian,Locke Davenport Huyer,Mauro Lo Rito,Robert A. Civitarese,Rachel D. Vanderlaan,Jun Wu,Lewis A. Reis,Abdul Momen,Saeed Akbari,Aric Pahnke,Ren-Ke Li,Christopher A. Caldarone,Milica Radisic,Milica Radisic +14 more
TL;DR: An elastic and microfabricated scaffold using a biodegradable polymer for functional tissue delivery via injection of human cell-derived patches to the epicardium, aorta and liver in a large-animal (porcine) model was achieved.
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The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes.
Anton Mihic,Jiao Li,Yasuo Miyagi,Mark Gagliardi,Shu-Hong Li,Jean W. Zu,Richard D. Weisel,Gordon Keller,Ren-Ke Li +8 more
TL;DR: This uniaxial stretching system may serve as a platform for the production of cardiac tissue-engineered constructs for translational applications and enhanced survival and engraftment of transplanted cells in the stretched constructs.
Journal ArticleDOI
A Glucagon-Like Peptide-1 Analog Reverses the Molecular Pathology and Cardiac Dysfunction of a Mouse Model of Obesity
Mohammad Hossein Noyan-Ashraf,Eric A. Shikatani,Irmgard Schuiki,Ilya Mukovozov,Jun Wu,Ren-Ke Li,Allen Volchuk,Lisa A. Robinson,Filio Billia,Daniel J. Drucker,Mansoor Husain +10 more
TL;DR: Weight-neutral treatment with a glucagon-like peptide-1 analog liraglutide activates several cardioprotective pathways, prevents HFD-induced insulin resistance and inflammation, reduces monocyte vascular adhesion, and improves cardiac function in vivo by activating AMP-activated protein kinase.
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Cell transplantation improves ventricular function after a myocardial infarction: a preclinical study of human unrestricted somatic stem cells in a porcine model.
Byung-Ok Kim,Hai Tian,Kriengchai Prasongsukarn,Jun Wu,Denis Angoulvant,Stephan Wnendt,Andreas Muhs,Dimitry Spitkovsky,Ren-Ke Li +8 more
TL;DR: This study suggests that the USSC implantation will be efficacious for cellular cardiomyoplasty and improved regional and global function of the porcine heart after a myocardial infarction.
Journal ArticleDOI
In Vivo Survival and Function of Transplanted Rat Cardiomyocytes
TL;DR: A cell suspension of cultured fetal and neonatal rat cardiomyocytes transplanted into the adult rat hindlimb formed contractile cardiac tissue in the subcutaneous connective tissue.