R
Renan P. Souza
Researcher at Universidade Federal de Minas Gerais
Publications - 110
Citations - 2548
Renan P. Souza is an academic researcher from Universidade Federal de Minas Gerais. The author has contributed to research in topics: Schizophrenia & Population. The author has an hindex of 23, co-authored 102 publications receiving 2059 citations. Previous affiliations of Renan P. Souza include Faculdade de Medicina da Universidade Federal de Minas Gerais & Universidade do Extremo Sul Catarinense.
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Journal ArticleDOI
Genetic association study between antipsychotic-induced weight gain and the melanocortin-4 receptor gene.
Nabilah I. Chowdhury,Arun K. Tiwari,Renan P. Souza,Clement C. Zai,Sajid A. Shaikh,Sheng Chen,Fang Liu,J A Lieberman,Herbert Y. Meltzer,Anil K. Malhotra,J.L. Kennedy,Daniel J. Müller +11 more
TL;DR: In vitro electrophoretic mobility-shift assay that suggested that the presence of the A-allele may create a transcription factor-binding site is suggested, and further investigation is warranted for both these exploratory findings.
Journal ArticleDOI
Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D
Shaunna L. Clark,Daniel E. Adkins,Karolina A. Aberg,John M. Hettema,Joseph L. McClay,Renan P. Souza,E J C G van den Oord +6 more
TL;DR: This study demonstrates the potential of GWAS to discover genes and pathways that could mediate adverse effects of antidepressant medication, and indicates that 10 SNPs in SACM1L mediated the effects of bupropion on sexual side-effects.
Journal ArticleDOI
Variants in the oxytocin gene and risk for schizophrenia.
Renan P. Souza,Renan P. Souza,Plabon Ismail,Herbert Y. Meltzer,James L. Kennedy,James L. Kennedy +5 more
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Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D
Daniel E. Adkins,Shaunna L. Clark,Karolina A. Aberg,John M. Hettema,József Bukszár,Joseph L. McClay,Renan P. Souza,E J C G van den Oord +7 more
TL;DR: This study demonstrates the potential of genome-wide association studies to discover genes and pathways that potentially mediate adverse effects of antidepressant medications and identifies genetic variation influencing susceptibility to citalopram-induced side effects.
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Influence of serotonin 3A and 3B receptor genes on clozapine treatment response in schizophrenia.
TL;DR: It is suggested that variants in the HTR3A receptor gene can play a role in the treatment outcome of clozapine in schizophrenia patients that are refractory or intolerant of typical antipsychotic therapy.