R
René Amstutz
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 25
Citations - 1071
René Amstutz is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Lithium & Crystal structure. The author has an hindex of 13, co-authored 25 publications receiving 1066 citations.
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Journal ArticleDOI
Probing the Helical Secondary Structure of Short‐Chain β‐Peptides
Dieter Seebach,Paola E. Ciceri,Mark Overhand,Bernhard Jaun,Dario Rigo,L. Oberer,Ulrich Hommel,René Amstutz,Hans Widmer +8 more
TL;DR: The results fully confirm predicted structural effects: incorporation of a single ‘wrong’ residue in the central position of the β-heptapeptide derivatives A fully confirms the helical structure of such β-peptides (previously discovered in pyridine solution).
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Tetrameric Cubic Structures of Two Solvated Lithium Enolates
TL;DR: The structures of the crystalline lithium enolates derived from 3, 3-dimethyl-2-butanone and from cyclopentanone have been determined by X-ray analysis as mentioned in this paper.
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Structures of Three Lithium Ester Enolates by X-ray Diffraction: Derivation of Reaction Path for Cleavage into Ketene and Alcoholate'
TL;DR: In this article, a detailed analysis of the geometry of the ester enolate grouping was derived, and the reaction path trajectory for the breakdown of this type of molecule can be derived.
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Structure and Reactivity of Five- and Six-Ring N, N-, N, O-, and O, O-acetals: A lesson in allylic 1, 3-strain (A1, 3 strain)
Dieter Seebach,Bernd Amatsch,René Amstutz,Albert K. Beck,Max Doler,Martin Egli,Robert Fitzi,Markus Gautschi,Bernardo Herradón,Pirmin C. Hidber,John J. Irwin,Rita Locher,Miguel A. Maestro,Thomas Maetzke,Antoni Mouriño,Elmar Pfammatter,Dietma A. Plattner,Christof P. Schickli,W. Bernd Schweizer,Paul Seiler,Gerhar Stucky,W. Petter,Jaime Escalante,Eusebio Juaristi,Delia Quintana,Carlos Miravitlles,Elies Molins +26 more
TL;DR: In this article, the X-ray structures of fifteen exocyclic Nacyl groups were compared with known structures of similar compounds and the conclusions drawn were considered relvant for a better understanding of the ever increasing role which amide groups play in stereoselective syntheses.
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Mechanistic Implications of the Tetrameric Cubic Structure of Lithium Enolates
TL;DR: The tetrameric cubic structure established for lithium enolates in the solid state is used as a model to discuss several facets of enolate chemistry: solubility, effects of cosolvents, addition to aldehyde and acid chloride, influence of mixed aggregates on diastereo- and enantioselectivities.