René Rezsohazy

TL;DR: Comparison with all the proka‐ryotic transposable elements sequenced so far revealed that the IS231 transposases share two conserved regions with those of 35 other insertion sequences of wide origins.

TL;DR: Impaired adipocyte differentiation contributes to the anti-adiposity effect of ApN, and a transgenic mouse model allowing persistent and moderate overexpression of native full-length ApN targeted to white adipose tissue is generated.

TL;DR: Biophysical studies demonstrate that entry of Penetratin into cells requires its binding to surface lipids but that binding and translocation are differentially affected by modifications of some physico-chemical properties of the peptide, like helical amphipathicity or net charge, and that internalization requires both lipid binding and other specific properties.

TL;DR: The molecular and cellular scale mechanisms underlying the diverse roles of the Hox transcription factors during morphogenesis and organogenesis are discussed.

TL;DR: Functional data gathered from IS231 A inEscherichia coli indicate a non-replicative mode of transposition, with a marked preference for specific targets, and a working model for DNA-protein interactions at the target site is proposed.