R
Renée A. Douma
Researcher at Academic Medical Center
Publications - 56
Citations - 2637
Renée A. Douma is an academic researcher from Academic Medical Center. The author has contributed to research in topics: Pulmonary embolism & Medicine. The author has an hindex of 20, co-authored 45 publications receiving 2133 citations. Previous affiliations of Renée A. Douma include University of Amsterdam.
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Journal ArticleDOI
Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study
Marc Philip Righini,Josien van Es,Paul L. den Exter,Pierre-Marie Roy,Franck Verschuren,Alexandre Ghuysen,Olivier Thierry Rutschmann,Olivier Sanchez,Morgan Jaffrelot,A Trinh-Duc,Catherine Le Gall,Farès Moustafa,Alessandra Principe,Anja A. van Houten,Marije Ten Wolde,Renée A. Douma,Germa Hazelaar,Petra M. G. Erkens,Klaas W Van Kralingen,Marco J. J. H. Grootenboers,Marc Durian,Y. Whitney Cheung,Guy Meyer,Henri Bounameaux,Menno V. Huisman,Pieter Willem Kamphuisen,Grégoire Le Gal +26 more
TL;DR: The combination of pretest clinical probability assessment with age-adjusted D-dimer cutoff was associated with a larger number of patients in whom PE could be considered ruled out with a low likelihood of subsequent clinical venous thromboembolism.
Journal ArticleDOI
Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: a retrospective analysis of three large cohorts
Renée A. Douma,Grégoire Le Gal,Maaike Sohne,Marc Philip Righini,Pieter Willem Kamphuisen,Arnaud Perrier,Marieke J. H. A. Kruip,Henri Bounameaux,Harry R. Büller,Pierre-Marie Roy +9 more
TL;DR: The age adjusted D-dimer cut-off point, combined with clinical probability, greatly increased the proportion of older patients in whom pulmonary embolism could be safely excluded.
Journal ArticleDOI
Diagnostic accuracy of conventional or age adjusted D-dimer cut-off values in older patients with suspected venous thromboembolism: systematic review and meta-analysis
Henrike J. Schouten,Geert-Jan Geersing,H.L. (Dineke) Koek,Nicolaas P.A. Zuithoff,Kristel J.M. Janssen,Renée A. Douma,Johannes J. M. van Delden,Karel G.M. Moons,Johannes B. Reitsma +8 more
TL;DR: The application of age adjusted cut-off values for D-dimer tests substantially increases specificity without modifying sensitivity, thereby improving the clinical utility of D- dimer testing in patients aged 50 or more with a non-high clinical probability.
Journal ArticleDOI
Performance of 4 Clinical Decision Rules in the Diagnostic Management of Acute Pulmonary Embolism: A Prospective Cohort Study
Renée A. Douma,Inge C. M. Mos,Petra M. G. Erkens,Tessa A.C. Nizet,Marc Durian,Marcel M. C. Hovens,Anja A. van Houten,Herman M.A. Hofstee,Frederikus A. Klok,Hugo ten Cate,Erik F. Ullmann,Harry R. Büller,Pieter Willem Kamphuisen,Menno V. Huisman +13 more
TL;DR: All 4 CDRs show similar performance for exclusion of acute PE in combination with a normal d-dimer result, and prospective validation indicates that the simplified scores may be used in clinical practice.
Journal ArticleDOI
Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded
Renée A. Douma,Melanie Tan,Roger E. G. Schutgens,Shannon M. Bates,Arnaud Perrier,Cristina Legnani,Douwe H. Biesma,Jeffrey S. Ginsberg,Henri Bounameaux,Gualtiero Palareti,Marc Carrier,Gerben C. Mol,Grégoire Le Gal,Pieter Willem Kamphuisen,Marc Philip Righini +14 more
TL;DR: The age-adjusted cut-off of the D-dimer combined with clinical probability greatly increases the proportion of older patients in whom deep vein thrombosis can be safely excluded.