R
Richard A. Lewis
Researcher at University of California, Santa Barbara
Publications - 18
Citations - 728
Richard A. Lewis is an academic researcher from University of California, Santa Barbara. The author has contributed to research in topics: Implantable cardioverter-defibrillator & Pyridine. The author has an hindex of 14, co-authored 17 publications receiving 657 citations. Previous affiliations of Richard A. Lewis include Yale University & University of California, San Diego.
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Journal ArticleDOI
Metal templated design of protein interfaces
Eric N. Salgado,Xavier Ambroggio,Jeffrey D. Brodin,Richard A. Lewis,Brian Kuhlman,F. Akif Tezcan +5 more
TL;DR: A rational design approach that mimics the time course of a hypothetical evolutionary pathway for the formation of stable protein assemblies through an initial metal coordination event and provides a route to engineer de novo protein interfaces and metal coordination environments that can be tuned through the extensive noncovalent bonding interactions in these interfaces.
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A Complete Family of Terminal Uranium Chalcogenides, [U(E)(N{SiMe3}2)3]− (E = O, S, Se, Te)
TL;DR: In the solid state, complexes 2-5 feature short U-E bond lengths, suggestive of actinide-ligand multiple bonding, and were fully characterized, including analysis by X-ray crystallography.
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Tuning the Reactivity of TEMPO by Coordination to a Lewis Acid: Isolation and Reactivity of MCl3(η1-TEMPO) (M = Fe, Al)
TL;DR: Control experiments indicated that neither MCl(3) (M = Al, Fe) nor TEMPO are capable of effecting the oxidation of alcohols independently.
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Metal-Mediated Self-Assembly of Protein Superstructures: Influence of Secondary Interactions on Protein Oligomerization and Aggregation
TL;DR: Crystallographic and hydrodynamic measurements on appropriately engineered cytochrome cb562 variants pinpoint the importance of a single salt-bridging arginine side chain in determining whether the protein monomers form a discrete Zn-induced tetrameric complex or heterogeneous aggregation.
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Synthesis and Characterization of an Iron(IV) Ketimide Complex
TL;DR: Both 1 and 2 are high spin and exhibit tetrahedral geometries in the solid state and complex 3 exhibits a diamagnetic ground state and a nearly square planar geometry about the Fe center.