R
Richard Bellamy
Researcher at Tan Tock Seng Hospital
Publications - 26
Citations - 2386
Richard Bellamy is an academic researcher from Tan Tock Seng Hospital. The author has contributed to research in topics: Population & Tuberculosis. The author has an hindex of 17, co-authored 26 publications receiving 2330 citations. Previous affiliations of Richard Bellamy include Wellcome Trust Centre for Human Genetics & University of London.
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Journal ArticleDOI
Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans.
Richard Bellamy,Cyril Ruwende,Tumani Corrah,Keith P. W. J. McAdam,Hilton Whittle,Adrian V. S. Hill +5 more
TL;DR: Genetic variation in NRAMP1 affects susceptibility to tuberculosis in West Africans, and subjects who were heterozygous for twoNRAMP1 polymorphisms in intron 4 and the 3' untranslated region of the gene were particularly overrepresented among those with tuberculosis.
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Susceptibility to mycobacterial infections: the importance of host genetics.
TL;DR: A genome-wide linkage study has been performed to identify genes exerting a major effect on tuberculosis susceptibility in the general population and linkages were found to markers on chromosomes 15 and X.
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The impact of malnutrition on survival and the CD4 count response in HIV-infected patients starting antiretroviral therapy.
TL;DR: The impact that malnutrition at the time of starting antiretroviral therapy (ART) has on survival and the CD4 count response is not known.
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Association of a Polymorphism in the P2X7 Gene with Tuberculosis in a Gambian Population
Cheuk M. Li,Cheuk M. Li,Sarah J. Campbell,Dinakantha S. Kumararatne,Richard Bellamy,Cyril Ruwende,Keith P. W. J. McAdam,Adrian V. S. Hill,David A. Lammas +8 more
TL;DR: A significant protective association against tuberculosis was found for 1 promoter SNP, at nucleotide position -762, which supports a role for ATP/P2X(7)-mediated host regulation of Mycobacterium tuberculosis infection.
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Assessment of the interleukin 1 gene cluster and other candidate gene polymorphisms in host susceptibility to tuberculosis.
TL;DR: Genetic susceptibility to tuberculosis among Gambians may be partly determined by genes in the IL1 gene cluster on chromosome 2, according to a study of tuberculosis cases and healthy blood donor controls.