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Richard D. Palmiter
Researcher at University of Washington
Publications - 455
Citations - 74646
Richard D. Palmiter is an academic researcher from University of Washington. The author has contributed to research in topics: Dopamine & Gene. The author has an hindex of 141, co-authored 444 publications receiving 69977 citations. Previous affiliations of Richard D. Palmiter include University of Pennsylvania & Howard Hughes Medical Institute.
Papers
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Book ChapterDOI
Insertion of growth hormone genes into pig embryos
Vernon G. Pursel,K. F. Miller,D. J. Bolt,Carl A. Pinkert,Robert E. Hammer,Richard D. Palmiter,Ralph L. Brinster +6 more
TL;DR: The persistent excess GH in transgenic pigs was detrimental to general health; lameness, lethargy, and gastric ulcers were the most prevalent problems.
Journal Article
Selective expression of class II E alpha d gene in transgenic mice.
TL;DR: It is demonstrated that dissociate expression of E alpha d within the macrophage lineage as well as within the B cell lineage, and evidence for a repressive element operative in B cells and macrophages is presented.
Posted ContentDOI
Gfral-expressing Neurons Suppress Food Intake via Aversive Pathways
Paul V. Sabatini,Henriette Frikke-Schmidt,Joe Arthurs,Desiree Gordian,Anita Patel,Jessica M. Adams,Jessica M. Adams,Jine Wang,Jine Wang,Sebastien Beck Jørgensen,David P. Olson,Richard D. Palmiter,Martin G. Myers,Randy J. Seeley +13 more
TL;DR: GFRAL neurons link non-meal-associated, pathophysiologic signals to the aversive suppression of nutrient uptake and absorption, suggesting that GFRal neurons primarily modulate gastric physiology and stimulate aversive responses.
Journal ArticleDOI
Interrogation by toxin.
TL;DR: A variation on an approach that uses diphtheria toxin to ablate specific cells in mice provides a better means of assessing biological function.
Journal ArticleDOI
Cotranslational sequestration of egg white proteins and placental lactogen inside membrane vesicles
TL;DR: Three mRNAs are translated in a modified reticulocyte lysate in the presence of radiolabeled amino acids and subjected the immunoprecipitated products to automated Edman degradation, raising the question of whether the egg white proteins are also synthesized as precursors and to examine the mechanisms involved in their secretion.