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Richard E. Lenski
Researcher at Michigan State University
Publications - 291
Citations - 40186
Richard E. Lenski is an academic researcher from Michigan State University. The author has contributed to research in topics: Population & Experimental evolution. The author has an hindex of 100, co-authored 283 publications receiving 36846 citations. Previous affiliations of Richard E. Lenski include Centers for Disease Control and Prevention & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Long-term experimental evolution in Escherichia coli. I. Adaptation and divergence during 2,000 generations.
TL;DR: The degree to which adaptation to a uniform environment among independently evolving asexual populations is associated with increasing divergence of those populations is assessed, consistent with theoretical expectations that do not invoke divergence due to multiple fitness peaks in a Wrightian evolutionary landscape.
Journal ArticleDOI
Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation.
TL;DR: In this article, the authors examined the dynamics of evolutionary adaptation, the genetic bases of adaptation, tradeoffs and the environmental specificity of adaptation and the origin and evolutionary consequences of mutators.
Journal ArticleDOI
Genome evolution and adaptation in a long-term experiment with Escherichia coli
Jeffrey E. Barrick,Dong Su Yu,Dong Su Yu,Sung Ho Yoon,Haeyoung Jeong,Tae Kwang Oh,Dominique Schneider,Richard E. Lenski,Jihyun F. Kim +8 more
TL;DR: Although adaptation decelerated sharply, genomic evolution was nearly constant for 20,000 generations, which is usually viewed as the signature of neutral evolution, but several lines of evidence indicate that almost all of these mutations were beneficial.
Journal ArticleDOI
Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations
TL;DR: The results support a Wrightian interpretation, in which chance events (mutation and drift) play an important role in adaptive evolution, as do the complex genetic interactions that underlie the structure of organisms.
Book ChapterDOI
The fate of competing beneficial mutations in an asexual population
TL;DR: The beneficial mutation rate and the distribution of mutational effects from changes in mean fitness in an evolving E. coli population are estimated.