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Richard L. Lammers
Researcher at Michigan State University
Publications - 54
Citations - 4317
Richard L. Lammers is an academic researcher from Michigan State University. The author has contributed to research in topics: Receptor tyrosine kinase & Receptor. The author has an hindex of 30, co-authored 51 publications receiving 4108 citations. Previous affiliations of Richard L. Lammers include Drexel University & Max Planck Society.
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Journal ArticleDOI
The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
E. Lowenstein,Roger J. Daly,A. Batzer,W. Li,B. Margolis,Richard L. Lammers,Axel Ullrich,Edward Y. Skolnik,Dafna Bar-Sagi,Joseph Schlessinger +9 more
TL;DR: Results suggest that GRB2/sem-5 plays a crucial role in a highly conserved mechanism for growth factor control of ras signaling.
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Identification of Trk Binding Sites for SHC and Phosphatidylinositol 3'-kinase and Formation of a Multimeric Signaling Complex
A Obermeier,Richard L. Lammers,K.H. Wiesmüller,Günther Jung,Joseph Schlessinger,Axel Ullrich +5 more
TL;DR: In vitro association of SHC and the p85 subunit of phosphatidylinositol 3'-kinase with the Trk tyrosine kinase was prevented only by phosphorylated Y-490- and Y-751-containing peptides, respectively.
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Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells
TL;DR: The formation of hybrid insulin/insulin-like growth factor-I(IGF-I) receptors in transfected rodent fibroblasts is demonstrated by examining reactivity with species- and receptor-specific monoclonal antibodies, and responses to these ligands were asymmetrical.
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Differential activities of protein tyrosine phosphatases in intact cells.
Richard L. Lammers,B Bossenmaier,D E Cool,Nicholas K. Tonks,Joseph Schlessinger,E H Fischer,Axel Ullrich +6 more
TL;DR: Clear differences in susceptibility of various forms of different RTKs to the action of PTP 1B, T-cell phosphatase (TC-PTP), and CD45 are demonstrated, which suggests cellular compartmentalization as a major factor defining activity and overall function.
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The Use of Simulation in Emergency Medicine: A Research Agenda
William F. Bond,Richard L. Lammers,Linda Spillane,Rebecca Smith-Coggins,Rosemarie Fernandez,Martin A. Reznek,John A. Vozenilek,James Gordon +7 more
TL;DR: The authors present here the consensus document from the task force regarding suggested areas for research, including opportunities to study reflective experiential learning, behavioral and team training, procedural simulation, computer screen-based simulation, and special topics in emergency medicine.