R
Richard W. Titball
Researcher at University of Exeter
Publications - 416
Citations - 23987
Richard W. Titball is an academic researcher from University of Exeter. The author has contributed to research in topics: Burkholderia pseudomallei & Clostridium perfringens. The author has an hindex of 79, co-authored 410 publications receiving 22484 citations. Previous affiliations of Richard W. Titball include Imperial College London & United States Army Medical Research Institute of Infectious Diseases.
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A gold nanoparticle-linked glycoconjugate vaccine against Burkholderia mallei
Anthony E. Gregory,Barbara M. Judy,Omar I Qazi,Carla A. Blumentritt,Katherine A. Brown,Andrew M. Shaw,Alfredo G. Torres,Richard W. Titball +7 more
TL;DR: In this paper, gold nanoparticles (AuNPs) were used with a glycoconjugate vaccine against B. mallei in the murine model of infection.
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Proteolytic Degradation of Human Antimicrobial Peptide LL-37 by Bacillus anthracis May Contribute to Virulence
TL;DR: Findings suggest that alongside the classical plasmid-based virulence determinants, extracellular metalloproteases of B. anthracis may play a role in survival in the host.
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A rapid, highly sensitive method for the detection of Francisella tularensis in clinical samples using the polymerase chain reaction
TL;DR: A highly sensitive method based on a nested polymerase chain reaction (PCR) for the FopA gene that has significant advantages over traditional methods for diagnosing F. tularensis infection in terms of speed, ease of use, reproducibility, and safety.
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Development of vaccines against burkholderia pseudomallei.
Natasha Patel,Laura Conejero,Melanie de Reynal,Anna Easton,Gregory J. Bancroft,Richard W. Titball +5 more
TL;DR: This review considers the multiple elements of melioidosis vaccine research including the immune responses required for protective immunity, the animal models available for preclinical testing of potential candidates, the different experimental vaccine strategies which are being pursued, and the obstacles and opportunities for eventual registration of a licensed vaccine in humans.
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The ABC Transporter Protein OppA Provides Protection against Experimental Yersinia pestis Infection
Mikio Tanabe,Helen S. Atkins,David N. Harland,Stephen J. Elvin,Anthony J. Stagg,Osman Mirza,Richard W. Titball,Richard W. Titball,Bernadette Byrne,Katherine A. Brown +9 more
TL;DR: The potential for ATP-binding cassette (ABC) transporter proteins to be exploited as novel vaccines against plague was evaluated and protection appeared to correlate with the level of immunoglobulin G antibody to OppA.