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Riikka Laitinen

Researcher at University of Eastern Finland

Publications -  39
Citations -  2252

Riikka Laitinen is an academic researcher from University of Eastern Finland. The author has contributed to research in topics: Dissolution & Amorphous solid. The author has an hindex of 19, co-authored 36 publications receiving 1805 citations. Previous affiliations of Riikka Laitinen include University of Otago & University of Copenhagen.

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Journal ArticleDOI

Emerging trends in the stabilization of amorphous drugs

Riikka Laitinen, +7 more
- 30 Aug 2013 - 
TL;DR: Formulation approaches such as the preparation of co-amorphous small-molecule mixtures and the use of mesoporous silicon and silica-based carriers are presented as potential means to increase the stability of amorphous pharmaceuticals.
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Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen.

Korbinian Löbmann, +5 more
- 15 Aug 2011 - 
TL;DR: A coamorphous drug/drug combination between the two nonsteroidal anti-inflammatory drugs, naproxen and γ-indomethacin, was prepared and investigated and it was suggested that the two drugs formed a heterodimer.
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Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement.

Korbinian Löbmann, +6 more
- 01 Nov 2013 - 
TL;DR: Amino acids appear as promising excipients to solve challenges connected with the stability and dissolution of amorphous drugs.
Journal ArticleDOI

Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions.

Korbinian Löbmann, +5 more
- 01 May 2012 - 
TL;DR: Improved stability in co-amorphous SVS-GPZ mixtures was concluded that this was attributable to the molecular level mixing of SVS with GPZ upon milling, and GPZ is acting as an anti-plasticizer in these mixtures.
Journal ArticleDOI

Amino acids as co-amorphous stabilizers for poorly water-soluble drugs--Part 2: molecular interactions.

Korbinian Löbmann, +6 more
- 01 Nov 2013 - 
TL;DR: The potential of amino acids as small molecular weight excipients in co-amorphous formulations to stabilize the amorphous form of a poorly water-soluble drug through strong and specific molecular interactions with the drug is shown.