R
Rina Zilkha-Falb
Researcher at Sheba Medical Center
Publications - 15
Citations - 231
Rina Zilkha-Falb is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: Experimental autoimmune encephalomyelitis & Neural stem cell. The author has an hindex of 6, co-authored 15 publications receiving 141 citations. Previous affiliations of Rina Zilkha-Falb include Weizmann Institute of Science.
Papers
More filters
Journal ArticleDOI
Humoral immune response in multiple sclerosis patients following PfizerBNT162b2 COVID19 vaccination: Up to 6 months cross-sectional study.
Anat Achiron,Mathilda Mandel,Sapir Dreyer-Alster,Gil Harari,Mark Dolev,Shay Menascu,David Magalashvili,Shlomo Flechter,Uri Givon,Diana Guber,Polina Sonis,Rina Zilkha-Falb,Michael Gurevich +12 more
TL;DR: In this article, the authors determined SARS-COV-2 IgG response up to 6 months following PfizerBNT162b2 vaccination in 414 multiple sclerosis (MS) patients and 89 healthy subjects.
Journal ArticleDOI
Post-CNS-inflammation expression of CXCL12 promotes the endogenous myelin/neuronal repair capacity following spontaneous recovery from multiple sclerosis-like disease
TL;DR: Elevated CXCL12 expression in the DG and CC of EAE-recovering mice is revealed, which persistently increases following spontaneous recovery even though CNS inflammation has subsided, highlighting the post-CNS-inflammation role of CxCL12 in augmenting the endogenous myelin/neuronal repair capacity in MS-like disease.
Journal ArticleDOI
The myelin-associated oligodendrocytic basic protein (MOBP) as a relevant primary target autoantigen in multiple sclerosis.
TL;DR: Studies showing that MOBP is as an important candidate target antigen in MS as the other widely studied target antigens, myelin basic protein (MBP), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG).
Journal ArticleDOI
'Multi-epitope-targeted' immune-specific therapy for a multiple sclerosis-like disease via engineered multi-epitope protein is superior to peptides.
Nathali Kaushansky,Nicole Kerlero de Rosbo,Rina Zilkha-Falb,Reut Yosef-Hemo,Lydia Cohen,Avraham Ben-Nun +5 more
TL;DR: Y-MSPc was superior to peptide(s) in concomitantly downregulating pathogenic T-cells reactive against multiple myelin antigens/epitopes, via inducing more effective, longer lasting peripheral regulatory mechanisms (cytokine shift, anergy, and Foxp3+ CTLA4+ regulatory T- cells).
Journal ArticleDOI
The Median Eminence, A New Oligodendrogenic Niche in the Adult Mouse Brain
TL;DR: It is shown that the median eminence (ME) of the hypothalamus comprises BrdU+ newly proliferating cells co-expressing NG2 (oligodendrocyte progenitors) and RIP (pre-myelinating oligodentrocytes) suggesting their differentiation toward mature oligodendROcytes (OLs).