R
Risto A. Kauppinen
Researcher at University of Manchester
Publications - 18
Citations - 1050
Risto A. Kauppinen is an academic researcher from University of Manchester. The author has contributed to research in topics: Relaxation (NMR) & Magnetic resonance imaging. The author has an hindex of 14, co-authored 18 publications receiving 926 citations. Previous affiliations of Risto A. Kauppinen include University of Eastern Finland & University of Minnesota.
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Journal ArticleDOI
Clinical Proton MR Spectroscopy in Central Nervous System Disorders
Gülin Öz,Jeffry R. Alger,Peter B. Barker,Robert Bartha,Alberto Bizzi,Chris Boesch,Patrick J. Bolan,Kevin M. Brindle,Cristina Cudalbu,Alp Dinçer,Ulrike Dydak,Uzay E. Emir,Jens Frahm,Ramón Gilberto González,Stephan Gruber,Rolf Gruetter,Rakesh K. Gupta,Arend Heerschap,Anke Henning,Hoby P. Hetherington,Franklyn A. Howe,Petra Susan Hüppi,Ralph E. Hurd,Kejal Kantarci,Dennis W. J. Klomp,Roland Kreis,Marijn J. Kruiskamp,Martin O. Leach,Alexander P. Lin,Peter R. Luijten,Małgorzata Marjańska,Andrew A. Maudsley,Dieter J. Meyerhoff,Carolyn E. Mountford,Sarah J. Nelson,M. Necmettin Pamir,Jullie W. Pan,Andrew C. Peet,Harish Poptani,S. Posse,Petra J. W. Pouwels,Eva-Maria Ratai,Brian D. Ross,Tom W. J. Scheenen,Christian Schuster,Ian C. P. Smith,Brian J. Soher,Ivan Tkáč,Daniel B. Vigneron,Risto A. Kauppinen +49 more
TL;DR: A summary of brain disorders in which proton (hydrogen 1 [(1)H]) magnetic resonance (MR) spectroscopy has an impact on patient management, together with a critical consideration of common data acquisition and processing procedures is presented.
Journal ArticleDOI
Effects of hematocrit and oxygen saturation level on blood spin‐lattice relaxation
TL;DR: Blood T1 showed a significant linear dependency on hematocrit and oxygen saturation, and oxygen dissolved in blood plasma in hyperoxygenated blood resulted in relaxation enhancement, comparable in size to that due to the change in oxygenation state of hemoglobin.
Journal ArticleDOI
Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: correlation with cell density.
Piia Valonen,Kimmo K. Lehtimäki,Tuula H. Väisänen,Mikko I. Kettunen,Olli Gröhn,Seppo Ylä-Herttuala,Risto A. Kauppinen,Risto A. Kauppinen +7 more
TL;DR: To study the characteristics of diffusion magnetic resonance imaging (MRI) contrast in a rat brain BT4C glioma during progression of ganciclovir‐thymidine kinase gene therapy‐induced programmed cell death (PCD) in vivo, MRI contrast is studied in vivo.
Journal ArticleDOI
Exchange-influenced T2ρ contrast in human brain images measured with adiabatic radio frequency pulses
Shalom Michaeli,Heidi Gröhn,Heidi Gröhn,Olli Gröhn,Olli Gröhn,Dennis J. Sorce,Risto A. Kauppinen,Charles S. Springer,Kamil Ugurbil,Michael Garwood +9 more
TL;DR: The methods presented assess T2ρ relaxation influenced by DA in tissue and provide a means to generate T1ρ contrast in MRI and assess differences in brain tissue water proton T2σ time constants.
Journal ArticleDOI
High‐resolution magic‐angle‐spinning 1H NMR spectroscopy reveals different responses in choline‐containing metabolites upon gene therapy‐induced programmed cell death in rat brain glioma
Piia Valonen,Julian L. Griffin,Kimmo K. Lehtimäki,Timo Liimatainen,Jeremy K. Nicholson,Olli Gröhn,Risto A. Kauppinen +6 more
TL;DR: Observations demonstrate that, while the in vivo 1H NMR peak at 3.23 ppm is indicative of cellular processes involved in apoptosis, the biochemical changes monitored by this resonance involve a number of different and chemically distinct metabolites.