Kamil Ugurbil

TL;DR: Progress made during the first half of the Human Connectome Project project in refining the methods for data acquisition and analysis provides grounds for optimism that the HCP datasets and associated methods and software will become increasingly valuable resources for characterizing human brain connectivity and function, their relationship to behavior, and their heritability and genetic underpinnings.

TL;DR: It is reported that visual stimulation produces an easily detectable (5-20%) transient increase in the intensity of water proton magnetic resonance signals in human primary visual cortex in gradient echo images at 4-T magnetic-field strength.

TL;DR: Using multi-modal magnetic resonance images from the Human Connectome Project and an objective semi-automated neuroanatomical approach, 180 areas per hemisphere are delineated bounded by sharp changes in cortical architecture, function, connectivity, and/or topography in a precisely aligned group average of 210 healthy young adults.

TL;DR: The Human Connectome Project (HCP) as discussed by the authors is a 5-year effort to characterize brain connectivity and function and their variability in healthy adults using diffusion imaging (dMRI), resting-state fMRI, task-evoked fMRI (T-fMRI), T1-and T2-weighted MRI for structural and myelin mapping, plus combined magnetoencephalography (MEG/EEG).

TL;DR: In this article, the authors discuss the basic quantitative features of the observed BOLD-based signal changes, including the signal amplitude and its magnetic field dependence and dynamic effects such as a pronounced oscillatory pattern that is induced in the signal from primary visual cortex during photic stimulation experiments.