[신간의 별자리x] 우리/미술, 그리고 ‘슬픔의 박물관’

Natural structural materials are built at ambient temperature from a fairly limited selection of components. They usually comprise hard and soft phases arranged in complex hierarchical architectures, with characteristic dimensions spanning from the nanoscale to the macroscale. The resulting materials are lightweight and often display unique combinations of strength and toughness, but have proven difficult to mimic synthetically. Here, we review the common design motifs of a range of natural structural materials, and discuss the difficulties associated with the design and fabrication of synthetic structures that mimic the structural and mechanical characteristics of their natural counterparts.

Bioinspired structural materials

A review of the biomaterials technologies for infection-resistant surfaces.

Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials.

https://www.cell.com/trends/biotechnology/pdf/S0167-7799(13)00030-9.pdf

Antibacterial surfaces: the quest for a new generation of biomaterials.

The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides

Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections.

Multilayered coating on titanium for controlled release of antimicrobial peptides for the prevention of implant-associated infections

Bone and nacre are the most-known biological hard tissues to materials researchers. Although highly mineralized, both bone and nacre are amazingly tough and exhibit remarkable inelasticity, properties that are still beyond the reach of many modern ceramic materials. Very interestingly, the two hard tissues seem to have adopted totally different structural strategies for achieving mechanical robustness. Starting from a true nanocomposite of the mineralized collagen fibril and following up to seven levels of hierarchical organization, bone is built on a structure with extreme complexity. In contrast, nacre possesses a structure of surprising simplicity. Polygonal mineral tablets of micrometer size are carefully cemented together into a macroscopic wonder. A comparative analysis of the structure-property relations in bone and nacre helps us to unveil the underlying mechanisms of this puzzling phenomenon. In this review, we critically compare the various levels of structures and their mechanical contributions...

Rizhi Wang

Papers

The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides

Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections.

Multilayered coating on titanium for controlled release of antimicrobial peptides for the prevention of implant-associated infections

Deformation and Fracture Mechanisms of Bone and Nacre

A composite coating by electrolysis-induced collagen self-assembly and calcium phosphate mineralization