Robbert A. Damveld

TL;DR: It is shown that Aspergillus niger also responds to cell wall stress by increasing chitin levels, and observations suggest thatcell wall stress in fungi may generally lead to activation of the chit in biosynthetic pathway.

TL;DR: In this article, the authors identify four loci involved in spore pigmentation of Aspergillus niger by using a combined genomic and classical complementation approach, and the loci whose mutation resulted in fawn, olive and brown color phenotypes were identified by complementation.

TL;DR: The results indicate that A. niger responds to cell wall stress by transcriptional activation of cell wall reinforcing genes including agsA and gfaA through an Rlm1p‐like transcription factor, and it is proposed that such a cell wall salvage mechanism is wide spread in filamentous fungi.

TL;DR: The results indicate that galactofuranose formation is important for fungal cell wall biosynthesis and represents an attractive target for the development of antifungals.

TL;DR: The first transcriptome analysis of Aspergillus niger exposed to the antifungal compounds caspofungin, an inhibitor of β-1,3-glucan synthesis, and fenpropimorph, which inhibits ergosterol synthesis is reported, showing that expression of the agsA gene encoding an α-1-3- glucan synthase is up-regulated by both compounds.