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Robert C. Griffiths

Researcher at University of Oxford

Publications -  137
Citations -  8105

Robert C. Griffiths is an academic researcher from University of Oxford. The author has contributed to research in topics: Coalescent theory & Population. The author has an hindex of 41, co-authored 135 publications receiving 7744 citations. Previous affiliations of Robert C. Griffiths include University of Utah & University of Texas Health Science Center at Houston.

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Journal ArticleDOI

Inferring Coalescence Times From DNA Sequence Data

Simon Tavaré, +3 more
- 01 Feb 1997 - 
TL;DR: Extensions are presented that allow for the effects of uncertainty in knowledge of population size and mutation rates, for variability in population sizes, for regions of different mutation rate, and for inference concerning the coalescence time of the entire population.
Journal ArticleDOI

Sampling Theory for Neutral Alleles in a Varying Environment

Robert C. Griffiths, +1 more
- 29 Jun 1994 - 
TL;DR: A coalescent approach to provide recursions for the probabilities of particular sample configurations is used, and a Monte Carlo method by which the solutions to such recursions can be approximated is described.
Journal ArticleDOI

Ancestral Inference in Population Genetics

Robert C. Griffiths, +1 more
- 01 Aug 1994 - 
TL;DR: In this article, the authors discuss some aspects of estimation and inference that arise in the study of such variability, focusing in particular on the estimation of substitution rates and their use in calibrating estimates of the time since the most recent common ancestor of a sample of sequences.
Journal ArticleDOI

Ancestral inference from samples of DNA sequences with recombination.

Robert C. Griffiths, +1 more
- 01 Jan 1996 - 
TL;DR: Ancestral inference procedures are discussed for estimating recombination and mutation rates; estimating the times to the most recent common ancestors along the sequences; estimating ages of mutations; and estimating the number of recombination events in the ancestry of the sample.
Journal Article

Archaic African and Asian lineages in the genetic ancestry of modern humans

Rosalind M. Harding, +7 more
- 01 Apr 1997 - 
TL;DR: Patterns of beta-globin diversity suggest extensive worldwide late Pleistocene gene flow and are not easily reconciled with a unidirectional migration out of Africa 100,000 years ago and total replacement of archaic populations in Asia.