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Robert G. Egbert
Researcher at Pacific Northwest National Laboratory
Publications - 24
Citations - 401
Robert G. Egbert is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Biology & Synthetic biology. The author has an hindex of 7, co-authored 17 publications receiving 324 citations. Previous affiliations of Robert G. Egbert include Lawrence Berkeley National Laboratory & University of Washington.
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Journal ArticleDOI
Fine-tuning gene networks using simple sequence repeats
Robert G. Egbert,Eric Klavins +1 more
TL;DR: A simple and general approach to rapidly tune gene networks in Escherichia coli using hypermutable simple sequence repeats embedded in the spacer region of the ribosome binding site is introduced, suggesting a new approach to optimizing gene networks via directed evolution.
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Specification and simulation of synthetic multicelled behaviors.
TL;DR: This work introduces a framework for the specification and simulation of multicelled behaviors that combines a simple simulation of microcolony growth and molecular signaling with a new specification language called gro and allows the researcher to explore the collective behaviors induced by high level descriptions of individual cell behaviors.
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Expanding the product profile of a microbial alkane biosynthetic pathway.
Matthew Harger,Lei Zheng,Austin Moon,Casey Ager,Ju Hye An,Chris Choe,Yi Ling Lai,Benjamin Mo,David M. Zong,Matthew D. Smith,Robert G. Egbert,Jeremy H. Mills,David Baker,Ingrid Swanson Pultz,Justin B. Siegel,Justin B. Siegel +15 more
TL;DR: The production of even chain length alkanes represents initial steps toward the expansion of this recently discovered microbial alkane production pathway to synthesize complex fuels.
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Synthetic Biology Tools for the Fast-Growing Marine Bacterium Vibrio natriegens.
Tanya Tschirhart,Vrinda Shukla,Erin E. Kelly,Zachary Schultzhaus,Erin NewRingeisen,Jeffrey S. Erickson,Zheng Wang,Whitney L. Garcia,Emaleigh Curl,Robert G. Egbert,Enoch Yeung,Gary J. Vora +11 more
TL;DR: The results indicate that while most parts and constructs work similarly in the two organisms, some deviate significantly and will aid in developing more robust synthetic biology principles and approaches for this non-model chassis.
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Towards Engineering Biological Systems in a Broader Context.
TL;DR: It is argued that synthetic circuits embedded in host organisms or designed ecologies informed by suitable measurement of biotic and abiotic environmental parameters could be used as engineering substrates to achieve target functions in complex environments.