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Robert Hudeček
Researcher at Masaryk University
Publications - 35
Citations - 640
Robert Hudeček is an academic researcher from Masaryk University. The author has contributed to research in topics: Uterine fibroids & Ulipristal acetate. The author has an hindex of 9, co-authored 33 publications receiving 572 citations.
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Journal ArticleDOI
Efficacy and safety of repeated use of ulipristal acetate in uterine fibroids
Jacques Donnez,Robert Hudeček,Olivier Donnez,Dace Matule,Hans Joachim Arhendt,János Zatik,Zaneta Kasilovskiene,Mihai Cristian Dumitrascu,Hervé Fernandez,David H. Barlow,Philippe Bouchard,Bart C.J.M. Fauser,Elke Bestel,Paul Terrill,Ian Osterloh,Ernest Loumaye +15 more
TL;DR: Repeated 12-week courses of daily oral ulipristal acetate (5 and 10 mg) effectively control bleeding and pain, reduce fibroid volume, and restore QoL in patients with symptomatic fibroids.
Journal ArticleDOI
Long-term medical management of uterine fibroids with ulipristal acetate
Jacques Donnez,Olivier Donnez,Dace Matule,Hans Joachim Ahrendt,Robert Hudeček,János Zatik,Zaneta Kasilovskiene,Mihai Cristian Dumitrascu,Hervé Fernandez,David H. Barlow,Philippe Bouchard,Bart C.J.M. Fauser,Elke Bestel,Ernest Loumaye +13 more
TL;DR: The results of this study demonstrate the efficacy and further support the safety profile of repeated intermittent treatment of symptomatic fibroids with ulipristal acetate and pain and QoL showed marked improvements from screening, even during the off-treatment intervals.
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Prevention of ovarian function damage by a GnRH analogue during chemotherapy in Hodgkin lymphoma patients
Martin Huser,Igor Crha,Pavel Ventruba,Robert Hudeček,Záková J,Lenka Šmardová,Zdeněk Král,Jiri Jarkovsky +7 more
TL;DR: Study showed a significant reduction of ovarian failure risk in women with HL treated with less aggressive CHT regimens plus a GnRH analogue.
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Survival and infertility treatment in male cancer patients after sperm banking.
Igor Crha,Pavel Ventruba,Záková J,Martin Huser,Barbara Kubešová,Robert Hudeček,Jiri Jarkovsky +6 more
TL;DR: Evaluated the relationship between sperm pathology and cancer diagnosis, determine the mortality rate, and evaluate the outcomes of the use of frozen sperm from the sperm bank found a significant number of patients survived.
Journal ArticleDOI
Effect of a Selective Progesterone Receptor Modulator on Induction of Apoptosis in Uterine Fibroids In Vivo
TL;DR: Treatment with ulipristal acetate induces apoptosis in uterine fibroid cells, and the effect of SPRM may contribute to their positive clinical effect on uterusine fibroids.