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Robert J. Gillies
Researcher at Moffitt Cancer Center
Publications - 520
Citations - 57585
Robert J. Gillies is an academic researcher from Moffitt Cancer Center. The author has contributed to research in topics: Cancer & Intracellular pH. The author has an hindex of 100, co-authored 502 publications receiving 45911 citations. Previous affiliations of Robert J. Gillies include University of Arizona & G. D. Searle & Company.
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Journal ArticleDOI
Radiomics: Images Are More than Pictures, They Are Data.
TL;DR: This report describes the process of radiomics, its challenges, and its potential power to facilitate better clinical decision making, particularly in the care of patients with cancer.
Journal ArticleDOI
Why do cancers have high aerobic glycolysis
TL;DR: In this article, the authors propose that persistent metabolism of glucose to lactate even in aerobic conditions is an adaptation to intermittent hypoxia in pre-malignant lesions, which leads to microenvironmental acidosis requiring evolution to phenotypes resistant to acid-induced cell toxicity.
Journal ArticleDOI
Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach
Hugo J.W.L. Aerts,Emmanuel Rios Velazquez,Ralph T.H. Leijenaar,Chintan Parmar,Patrick Grossmann,Sara Carvalho,Sara Cavalho,Johan Bussink,René Monshouwer,Benjamin Haibe-Kains,Derek H. F. Rietveld,Frank J. P. Hoebers,Michelle M. Rietbergen,C. René Leemans,Andre Dekker,John Quackenbush,Robert J. Gillies,Philippe Lambin +17 more
TL;DR: The data suggest that radiomics identifies a general prognostic phenotype existing in both lung and head-and-neck cancer, which may have a clinical impact as imaging is routinely used in clinical practice, providing an unprecedented opportunity to improve decision-support in cancer treatment at low cost.
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Radiomics: extracting more information from medical images using advanced feature analysis.
Philippe Lambin,Emmanuel Rios-Velazquez,Ralph T.H. Leijenaar,Sara Carvalho,Ruud G.P.M. van Stiphout,Patrick V. Granton,Catharina M.L. Zegers,Robert J. Gillies,Ronald Boellard,Andre Dekker,Hugo J.W.L. Aerts,Hugo J.W.L. Aerts +11 more
TL;DR: Radiomics--the high-throughput extraction of large amounts of image features from radiographic images--addresses this problem and is one of the approaches that hold great promises but need further validation in multi-centric settings and in the laboratory.
Journal ArticleDOI
Radiomics: the process and the challenges
Virendra Kumar,Yuhua Gu,Satrajit Basu,Anders Berglund,Steven A. Eschrich,Matthew B. Schabath,Kenneth M. Forster,Hugo J.W.L. Aerts,Hugo J.W.L. Aerts,Andre Dekker,David Fenstermacher,Dmitry B. Goldgof,Lawrence O. Hall,Philippe Lambin,Yoganand Balagurunathan,Robert A. Gatenby,Robert J. Gillies +16 more
TL;DR: "Radiomics" refers to the extraction and analysis of large amounts of advanced quantitative imaging features with high throughput from medical images obtained with computed tomography, positron emission tomography or magnetic resonance imaging, leading to a very large potential subject pool.