R
Robert S. Elkeles
Researcher at Imperial College London
Publications - 55
Citations - 2082
Robert S. Elkeles is an academic researcher from Imperial College London. The author has contributed to research in topics: Diabetes mellitus & Type 2 diabetes. The author has an hindex of 21, co-authored 55 publications receiving 2011 citations. Previous affiliations of Robert S. Elkeles include St Mary's Hospital.
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Journal ArticleDOI
High prevalence of gestational diabetes in women from ethnic minority groups.
Anne Dornhorst,C.M. Paterson,J.S.D. Nicholls,Jane Wadsworth,D.C. Chiu,Robert S. Elkeles,Desmond G. Johnston,R.W. Beard +7 more
TL;DR: Ethnic origin has a major influence on the prevalence of gestational diabetes and the importance of other risk factors varies between ethnic groups, which have important implications for the screening of women in pregnancy.
Journal ArticleDOI
Coronary calcium measurement improves prediction of cardiovascular events in asymptomatic patients with type 2 diabetes: the PREDICT study
Robert S. Elkeles,Ian F. Godsland,Michael D. Feher,Michael B. Rubens,Michael Roughton,F. Nugara,Steve E. Humphries,William Richmond,Marcus Flather +8 more
TL;DR: Measurement of CACS is a powerful predictor of cardiovascular events in asymptomatic patients with T2DM and can further enhance prediction provided by established risk models.
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Variation in the PPARα gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects
David M. Flavell,I. Pineda Torra,Yalda Jamshidi,David M. Evans,J. R. Diamond,Robert S. Elkeles,Sarah R. Bujac,George J. Miller,Philippa J. Talmud,Bart Staels,S.E. Humphries +10 more
TL;DR: It is demonstrated that PPARα is a link between diabetes and dyslipidaemia, and so could influence the risk of coronary artery disease, the greatest cause of morbidity and mortality in Type II diabetes.
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Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women
Steve E. Humphries,David Gable,Jackie A. Cooper,Helen Ireland,Jeffrey W. Stephens,Steven J. Hurel,Ka Wah Li,Jutta Palmen,Michelle A. Miller,Francesco P. Cappuccio,Robert S. Elkeles,Ian F. Godsland,George J. Miller,Philippa J. Talmud +13 more
TL;DR: It is confirmed that TCF7L2 genotype is a major risk factor for development of T2D and extended previous observations to other ethnic groups, and stronger associations were found for the IVS4G > T in all studies.
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The effects of metformin on glycemic control and serum lipids in insulin-treated NIDDM patients with suboptimal metabolic control.
TL;DR: Metformin, when given as adjunctive therapy, was well tolerated and improved glycemic control and lipid concentrations in patients with insulin-treated NIDDM whose diabetes was poorly controlled and these improvements could be maintained over the long term.