Roberta Colicchio

TL;DR: Marked dysbiosis and an abundance of a peculiar CD-Nf strain characterize the duodenal microbiome in active CD patients thus suggesting that the CD-associated microbiota could contribute to the many inflammatory signals in this disorder.

TL;DR: Data herein indicated that both pomegranate aril and peel extracts have an effective antimicrobial activity, as evidenced by the inhibitory effect on the bacterial growth of two important human pathogens, including Staphylococcus aureus and Escherichia coli, which are often involved in foodborne illness.

TL;DR: DNA–protein interaction studies demonstrated that 2‐oxoglutarate, a product of the catabolic reaction of the NADP‐GDH and an intermediate of the tricarboxylic acid (TCA) cycle, inhibits binding of GdhR to gdhA P2.

TL;DR: In vitro microbiological tests demonstrate that the hydroalcoholic extracts of pomegranate juice and peel are able to contrast the main cariogenic bacteria involved in tooth decay.

TL;DR: It is demonstrated that infected progenitors with trisomy 21 have a more pronounced perturbation of immune response genes than infected euploid cells, and that their progenitor cells are more susceptible to hydroperoxide-induced oxidative stress and infection with Bartonella henselae.