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Roberto Queiroga Lautner
Researcher at Universidade Federal de Minas Gerais
Publications - 11
Citations - 695
Roberto Queiroga Lautner is an academic researcher from Universidade Federal de Minas Gerais. The author has contributed to research in topics: Receptor & Angiotensin II. The author has an hindex of 8, co-authored 11 publications receiving 596 citations. Previous affiliations of Roberto Queiroga Lautner include National Institute of Standards and Technology.
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Journal ArticleDOI
Discovery and Characterization of Alamandine A Novel Component of the Renin–Angiotensin System
Roberto Queiroga Lautner,Daniel C. Villela,Rodrigo A. Fraga-Silva,Neiva Caldeira Silva,Thiago Verano-Braga,Fabiana P. Costa-Fraga,Joachim Jankowski,Vera Jankowski,Frederico B. De Sousa,Andréia Carvalho Alzamora,Everton Rocha Soares,Claudiane Maria Barbosa,Frank Kjeldsen,Aline C. Oliveira,Janaina F Braga,Silvia Q Savergnini,Gisele Maia,Antonio A B Peluso,Danielle G. Passos-Silva,Anderson J. Ferreira,Fabiana Alves,Almir S. Martins,Mohan K. Raizada,Renata D. Paula,Daisy Motta-Santos,Friederike Kemplin,Adriano Marçal Pimenta,Natalia Alenina,Rubén D. Sinisterra,Michael Bader,Maria José Campagnole-Santos,Robson A.S. Santos +31 more
TL;DR: Alamandine produces several physiological actions that resemble those produced by angiotensin-(1–7), including vasodilation, antifibrosis, antihypertensive, and central effects and may help to develop new therapeutic strategies for treating human cardiovascular diseases and other related disorders.
Journal ArticleDOI
Vascular Relaxation, Antihypertensive Effect, and Cardioprotection of a Novel Peptide Agonist of the Mas Receptor
Silvia Q Savergnini,Merav Beiman,Roberto Queiroga Lautner,Vanice de Paula-Carvalho,Kyan J. Allahdadi,Dalton Caires Pessoa,Fabiana P. Costa-Fraga,Rodrigo A. Fraga-Silva,Gady Cojocaru,Yossi Cohen,Michael Bader,Alvair P. Almeida,Galit Rotman,Robson A.S. Santos +13 more
TL;DR: The results presented here indicate that the novel Mas agonist, CGEN-856S, might have a therapeutic value, because it induces vasorelaxing, antihypertensive, and cardioprotective effects.
Journal ArticleDOI
Angiotensin-Converting Enzyme 2 Activation Improves Endothelial Function
Rodrigo A. Fraga-Silva,Fabiana P. Costa-Fraga,Tatiane M. Murça,Patrícia L. Moraes,Augusto Martins Lima,Roberto Queiroga Lautner,Carlos H. Castro,Célia Maria de Almeida Soares,Clayton Luiz Borges,Ana Paula Nadu,Marilene L. Oliveira,Vinayak Shenoy,Michael J. Katovich,Robson A.S. Santos,Mohan K. Raizada,Anderson J. Ferreira +15 more
TL;DR: Results showed that chronic XNT administration improves the endothelial function of hypertensive and diabetic rat vessels by attenuation of the oxidative stress and it is a potential target for treating cardiovascular disease.
Journal ArticleDOI
AVE 0991, a non-peptide mimic of angiotensin-(1-7) effects, attenuates pulmonary remodelling in a model of chronic asthma.
Maria da Glória Rodrigues-Machado,Giselle Santos Magalhães,Jefferson Alcântara Cardoso,Lucas M. Kangussu,A Murari,Marcelo Vidigal Caliari,Marilene L. Oliveira,Denise Carmona Cara,M L M Noviello,Fúlvia D. Marques,J M Pereira,Roberto Queiroga Lautner,Robson A.S. Santos,Maria José Campagnole-Santos +13 more
TL;DR: The effect of AVE on pulmonary remodelling in a murine model of ovalbumin (OVA)‐induced chronic allergic lung inflammation is investigated.
Journal ArticleDOI
Structure-function studies of Tityus serrulatus hypotensin-I (TsHpt-I): a new agonist of B2 kinin receptor.
Thiago Verano-Braga,Flávia Figueiredo-Rezende,Marcella N. Melo,Roberto Queiroga Lautner,Enéas Ricardo de Morais Gomes,Leonor T. Mata-Machado,Antonela Murari,Cibele Rocha-Resende,Maria Elena de Lima,Silvia Guatimosim,Robson A.S. Santos,Adriano Marçal Pimenta +11 more
TL;DR: It is demonstrated that the minimization of the primary structure of TsHpt-I does not significantly alter the biological effects of this native peptide, which could be of interest for biotechnological purposes.