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Robin D. Knight
Researcher at Princeton University
Publications - 16
Citations - 8021
Robin D. Knight is an academic researcher from Princeton University. The author has contributed to research in topics: Genetic code & Transfer RNA. The author has an hindex of 15, co-authored 16 publications receiving 7227 citations. Previous affiliations of Robin D. Knight include University of Colorado Boulder.
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Parallel evolution of the genetic code in arthropod mitochondrial genomes.
TL;DR: This work has investigated the evolution of the genetic code in the arthropods and found several events of parallel evolution in which the AGG codon was reassigned between serine and lysine, and correlated evolution between theArthropod genetic codes and the tRNA-Lys/-Ser, which show specific point mutations at the anticodons.
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The Early Evolution of the Genetic Code
TL;DR: A diversity of events suggests that an explanation for the fixation of the canonical code in the LUCA will require more historical reconstruction than reasoning from chemical principles.
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Rhyme or reason: RNA-arginine interactions and the genetic code
TL;DR: A statistical analysis of arginine-binding RNA aptamers provides the strongest support for an intrinsic affinity between any amino acid and its codons.
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Measuring adaptation within the genetic code.
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Guilt by association: the arginine case revisited.
TL;DR: The previous analysis of arginine binding sites is defended and extended, and a model for the maintenance of codon-amino acid interactions through the evolution of amino acids from ribozyme cofactors into the building blocks of proteins is proposed.