R
Rocio Ortiz-Lopez
Researcher at Monterrey Institute of Technology and Higher Education
Publications - 138
Citations - 4235
Rocio Ortiz-Lopez is an academic researcher from Monterrey Institute of Technology and Higher Education. The author has contributed to research in topics: Population & Gene. The author has an hindex of 25, co-authored 123 publications receiving 3720 citations. Previous affiliations of Rocio Ortiz-Lopez include Baylor College of Medicine & Universidad Autónoma de Nuevo León.
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Journal ArticleDOI
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation
Qiuyun Chen,Glenn E. Kirsch,Danmei Zhang,Ramon Brugada,Josep Brugada,Pedro Brugada,Domenico Potenza,Angel Moya,Martin Borggrefe,Günter Breithardt,Rocio Ortiz-Lopez,Zhiqing Wang,Charles Antzelevitch,Richard E. O'Brien,Eric Schulze-Bahr,Mark T. Keating,Jeffrey A. Towbin,Qing Wang +17 more
TL;DR: It is shown that sodium channels with the missense mutation recover from inactivation more rapidly than normal and that the frameshift mutation causes the sodium channel to be non-functional.
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Evidence for a Dystrophin Missense Mutation as a Cause of X-Linked Dilated Cardiomyopathy
TL;DR: A novel missense mutation in exon 9 of dystrophin causing an abnormality at H1 leads to the cardiospecific phenotype of XLCM.
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Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer.
TL;DR: In this paper, the authors discuss mechanisms of DNA damage and repair, genes related to these functions, and the diagnosis methods designed and under research for detection of breast cancer patients with increased radiosensitivity.
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Evidence for a recessive PMP22 point mutation in Charcot–Marie–Tooth disease type 1A
Benjamin B. Roa,Carlos A. Garcia,Liu Pentao,James M. Killian,Barbara J. Trask,Ueli Suter,G. Jackson Snipes,Rocio Ortiz-Lopez,Eric M. Shooter,Pragna Patel,James R. Lupski +10 more
TL;DR: A severely affected CMT1 patient is identified who is a compound heterozygote for a recessive PMP22 point mutation, and a 1.5 Mb deletion in 17p11.2–p12 is identified, suggesting that point mutations in PMP 22 can result in dominant and recessive alleles contributing to CMT 1A.
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The Tumor-on-Chip: Recent Advances in the Development of Microfluidic Systems to Recapitulate the Physiology of Solid Tumors
Grissel Trujillo-de Santiago,Brenda Giselle Flores-Garza,Jorge Alfonso Tavares-Negrete,Itzel Montserrat Lara-Mayorga,Ivonne González-Gamboa,Yu Shrike Zhang,Augusto Rojas-Martinez,Rocio Ortiz-Lopez,Mario Moises Alvarez +8 more
TL;DR: The aim is to provide the readers with an overview of the state of the art on this particular theme and to illustrate the toolbox available today for engineering tumor-like structures (and their environments) in microfluidic devices.