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Rodrigo F.M. de Almeida

Researcher at University of Lisbon

Publications -  81
Citations -  3958

Rodrigo F.M. de Almeida is an academic researcher from University of Lisbon. The author has contributed to research in topics: Membrane & Lipid bilayer. The author has an hindex of 30, co-authored 76 publications receiving 3573 citations. Previous affiliations of Rodrigo F.M. de Almeida include Instituto Superior Técnico & Wageningen University and Research Centre.

Papers
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Journal ArticleDOI

Sphingomyelin/phosphatidylcholine/cholesterol phase diagram: boundaries and composition of lipid rafts

Rodrigo F.M. de Almeida, +2 more
- 01 Oct 2003 - 
TL;DR: The diagrams here described are used to rationalize literature results, some of them apparently discrepant, and to discuss lipid rafts within the framework of liquid-ordered/liquid-disordered phase coexistence.
Journal ArticleDOI

Lipid rafts have different sizes depending on membrane composition: a time-resolved fluorescence resonance energy transfer study.

Rodrigo F.M. de Almeida, +4 more
- 04 Mar 2005 - 
TL;DR: It is concluded that lipid-lipid interactions alone can originate lipid rafts on very different length scales and the conclusions presented here are consistent with the literature concerning both model systems and cell membrane studies.
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Ceramide-Domain Formation and Collapse in Lipid Rafts: Membrane Reorganization by an Apoptotic Lipid

Liana C. Silva, +5 more
- 15 Jan 2007 - 
TL;DR: It is revealed that low palmitoyl-ceramide (PCer) concentrations strongly changed both the biophysical properties and lipid lateral organization of the ternary mixtures in the low-to-intermediate Chol/PSM-, small raft size range and in the high Chol-PSM- large raft domains range, where Chol completely abolished the effect of PCer by competing for PSM association.
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Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy

Gwendolyn Barceló-Coblijn, +9 more
- 06 Dec 2011 - 
TL;DR: It is proposed that the regulation of SMS activity in tumor cells is a critical upstream event in 2OHOA antitumor mechanism, which also explains its specificity for cancer cells, its potency, and the lack of undesired side effects.
Journal ArticleDOI

Membrane lipid domains and rafts: current applications of fluorescence lifetime spectroscopy and imaging

Rodrigo F.M. de Almeida, +2 more
- 01 Feb 2009 - 
TL;DR: It is shown how the use of time-resolved fluorescence, with the adequate parameters and probes, helps elucidating the type, number, fraction, composition and size of lipid phases and domains in multicomponent model systems.