R
Roger A. Schultz
Researcher at University of Texas Southwestern Medical Center
Publications - 57
Citations - 26443
Roger A. Schultz is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 27, co-authored 57 publications receiving 24988 citations. Previous affiliations of Roger A. Schultz include University of Texas at Dallas.
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Journal ArticleDOI
Small scale genetic alterations contribute to increased mutability at the X-linked Hprt locus in vivo in Blm hypomorphic mice.
Irina V. Tereshchenko,Yanping Chen,Lisa D. McDaniel,Roger A. Schultz,Jay A. Tischfield,Changshun Shao,Changshun Shao +6 more
TL;DR: Both large scale and small scale genetic alterations are elevated when BLM is reduced, which may contribute to loss of function of tumor suppressor genes and subsequent tumorigenesis.
Journal ArticleDOI
Correction of the Bloom Syndrome Cellular Phenotypes
TL;DR: Results support the notion that BLM is a defect in which short stature, chromosome instability and cancer predisposition are all associated with an error in DNA replication.
Journal ArticleDOI
TERF2-XPF: caught in the middle; beginnings from the end.
TL;DR: It is demonstrated that overexpression of TERF2 produces mouse phenotypes similar to those associated with xeroderma pigmentosum, such as cellular hypersensitivity to UV radiation and DNA crosslinking agents, and telomere shortening and chromosome instability in response to DNA damage.
Journal ArticleDOI
Validation of XP-C pathogenic variations in archival material from a live XP patient.
TL;DR: The serendipitous reacquisition of an XP individual in whom genetic defects were previously characterized in archival material allowed confirmation of the defects as well as a direct analysis of the consequences of these defects on mRNA, mRNA expression and on cellular phenotypes.
Journal Article
Fourth International Workshop on Human Chromosome 15 Mapping, Genome Database, Baltimore, MD, October 28 1997
Cynthia C. Morton,S. L. Christian,Timothy A. Donlon,Daniel J. Driscoll,J. K. Fink,J. M. Gabriel,Garrett Gotway,John M. Greally,M. P. Hitchins,H. C. Howard,Y. Ji,S. Leonard,T. Lerner,E. Magenis,Sue Malcolm,Tohru Ohta,S. Rainier,M. Rees,B. Riley,Wendy P. Robinson,Shinji Saitoh,Roger A. Schultz,S. Sell,J. D. Sharp,C. Talbot,Ronald J. Trent,Rachel Wevrick,Robert D. Nicholls +27 more