R
Rohtesh S. Mehta
Researcher at University of Texas MD Anderson Cancer Center
Publications - 160
Citations - 3383
Rohtesh S. Mehta is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 19, co-authored 122 publications receiving 1978 citations. Previous affiliations of Rohtesh S. Mehta include University of Texas at Austin & University of Pittsburgh.
Papers
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Journal ArticleDOI
Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
Enli Liu,David Marin,Pinaki P. Banerjee,Homer A. Macapinlac,Philip A. Thompson,Rafet Basar,Lucila Nassif Kerbauy,Bethany J Overman,Peter F. Thall,Mecit Kaplan,Vandana Nandivada,Indresh Kaur,Ana Karen Nunez Cortes,Kai Cao,May Daher,Chitra Hosing,Evan N. Cohen,Partow Kebriaei,Rohtesh S. Mehta,Sattva S. Neelapu,Yago Nieto,Michael Wang,William G. Wierda,Michael J. Keating,Richard E. Champlin,Elizabeth J. Shpall,Katayoun Rezvani +26 more
TL;DR: Among 11 patients with relapsed or refractory CD19-positive cancers, a majority had a response to treatment with CAR-NK cells without the development of major toxic effects.
Journal ArticleDOI
Chimeric Antigen Receptor Expressing Natural Killer Cells for the Immunotherapy of Cancer.
TL;DR: Preclinical data is reviewed on the development of CAR-NK cells, advantages, disadvantages, and current obstacles to their clinical use that can provide a potential source of allogeneic “off-the-shelf” cellular therapy.
Journal ArticleDOI
Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation.
Uday R. Popat,Rohtesh S. Mehta,Katy Rezvani,Patricia S. Fox,Kayo Kondo,David Marin,Ian McNiece,Betul Oran,Chitra Hosing,Amanda Olson,Simrit Parmar,Nina Shah,Michael Andreeff,Partow Kebriaei,Indreshpal Kaur,Eric Yvon,Marcos de Lima,Laurence J.N. Cooper,Priti Tewari,Richard E. Champlin,Yago Nieto,Borje S. Andersson,Amin M. Alousi,Roy B. Jones,Muzaffar H. Qazilbash,Qaiser Bashir,Stefan O. Ciurea,Sairah Ahmed,Paolo Anderlini,Doyle Bosque,Catherine M. Bollard,Jeffrey J. Molldrem,Julianne Chen,Gabriela Rondon,Mike Thomas,Leonard D. Miller,Steve Wolpe,Paul J. Simmons,Simon P. Robinson,Patrick A. Zweidler-McKay,Elizabeth J. Shpall +40 more
TL;DR: Findings support ex vivo fucosylation of multipotent CD34(+) CB cells as a clinically feasible means to improve engraftment efficiency in the double CBT setting.
Journal ArticleDOI
Immune reconstitution post allogeneic transplant and the impact of immune recovery on the risk of infection.
TL;DR: The process of immune reconstitution post-HCT that begins with the innate system and is followed by recovery of adaptive immunity is explained and various strategies that are being tested are allude to.
Journal ArticleDOI
New and emerging therapies for acute and chronic graft versus host disease.
LaQuisa Hill,Amin M. Alousi,Partow Kebriaei,Rohtesh S. Mehta,Katayoun Rezvani,Elizabeth J. Shpall +5 more
TL;DR: There is an unmet need for development of newer treatment strategies for both acute and chronic GVHD to improve long-term post-transplant outcomes and quality of life for HSCT recipients.