L
Lucila Nassif Kerbauy
Researcher at University of Texas MD Anderson Cancer Center
Publications - 43
Citations - 1593
Lucila Nassif Kerbauy is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 25 publications receiving 733 citations. Previous affiliations of Lucila Nassif Kerbauy include University of São Paulo & University of Texas at Austin.
Papers
More filters
Journal ArticleDOI
Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
Enli Liu,David Marin,Pinaki P. Banerjee,Homer A. Macapinlac,Philip A. Thompson,Rafet Basar,Lucila Nassif Kerbauy,Bethany J Overman,Peter F. Thall,Mecit Kaplan,Vandana Nandivada,Indresh Kaur,Ana Karen Nunez Cortes,Kai Cao,May Daher,Chitra Hosing,Evan N. Cohen,Partow Kebriaei,Rohtesh S. Mehta,Sattva S. Neelapu,Yago Nieto,Michael Wang,William G. Wierda,Michael J. Keating,Richard E. Champlin,Elizabeth J. Shpall,Katayoun Rezvani +26 more
TL;DR: Among 11 patients with relapsed or refractory CD19-positive cancers, a majority had a response to treatment with CAR-NK cells without the development of major toxic effects.
Journal ArticleDOI
Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells
May Daher,Rafet Basar,Elif Gokdemir,Natalia Baran,Nadima Uprety,Ana Karen Nunez Cortes,Mayela Mendt,Lucila Nassif Kerbauy,Pinaki P. Banerjee,Mayra Shanley,Nobuhiko Imahashi,Li Li,Francesca Lorraine Wei Inng Lim,Mohsen Fathi,Ali Rezvan,Vakul Mohanty,Yifei Shen,Hila Shaim,Junjun Lu,Gonca Ozcan,Emily Ensley,Mecit Kaplan,Vandana Nandivada,Mustafa H Bdiwi,Sunil Acharya,Yuanxin Xi,Xinhai Wan,Duncan Mak,Enli Liu,Xin Ru Jiang,Sonny Ang,Luis Muniz-Feliciano,Ye Li,Jing Wang,Shahram Kordasti,Nedyalko Petrov,Navin Varadarajan,David Marin,Lorenzo Brunetti,Richard Skinner,Shangrong Lyu,Leiser Silva,Rolf Turk,Mollie S. Schubert,Garrett R. Rettig,Matthew S. McNeill,Gavin Kurgan,Mark A. Behlke,Heng Li,Natalie W. Fowlkes,Ken Chen,Marina Konopleva,Richard E. Champlin,Elizabeth J. Shpall,Katayoun Rezvani +54 more
TL;DR: It is concluded that targeting a cytokine checkpoint further enhances the antitumor activity of IL-15 secreting armored CAR-NK cells by promoting their metabolic fitness and anti-tumorActivity.
Journal ArticleDOI
Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells.
Hila Shaim,Mayra Shanley,Rafet Basar,May Daher,Joy Gumin,Daniel Zamler,Nadima Uprety,Fang Wang,Yuefan Huang,Konrad Gabrusiewicz,Qi Miao,Jinzhuang Dou,Abdullah Alsuliman,Lucila Nassif Kerbauy,Sunil Acharya,Vakul Mohanty,Mayela Mendt,Sufang Li,Jun Jun Lu,Jun Wei,Natalie W. Fowlkes,Elif Gokdemir,Emily Ensley,Mecit Kaplan,Cynthia Kassab,Li Li,Gonca Ozcan,Pinaki P. Banerjee,Yifei Shen,April L. Gilbert,Corry M. Jones,Mustafa H Bdiwi,Ana K. Nunez-Cortes,Enli Liu,Jun Yu,Nobuhiko Imahashi,Luis Muniz-Feliciano,Ye Li,Jian Hu,Giulio Draetta,David Marin,Dihua Yu,Stephan Mielke,Matthias Eyrich,Richard E. Champlin,Ken Chen,Frederick F. Lang,Elizabeth J. Shpall,Amy B. Heimberger,Katayoun Rezvani +49 more
TL;DR: The authors showed that GSCs, but not normal astrocytes, are sensitive to lysis by healthy allogeneic natural killer (NK) cells in vitro, and suggested the αv integrin/TGF-β axis as a potentially useful therapeutic target in GBM.
Journal ArticleDOI
Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood-Derived NK Cells Facilitates CAR-like Responses Against CD30+ Malignancies.
Lucila Nassif Kerbauy,Lucila Nassif Kerbauy,Nancy D. Marin,Mecit Kaplan,Pinaki P. Banerjee,Melissa M. Berrien-Elliott,Michelle Becker-Hapak,Rafet Basar,Mark P. Foster,Luciana Garcia Melo,Carly Neal,Ethan McClain,May Daher,Ana Karen Nunez Cortes,Sweta Desai,Francesca Lorraine Wei Inng Lim,Mayela Mendt,Timothy Schappe,Li Li,Hila Shaim,Mayra Shanley,Emily Ensley,Nadima Uprety,Pamela Wong,Enli Liu,Sonny Ang,Rong Cai,Vandana Nandivada,Vakul Mohanty,Qi Miao,Yifei Shen,Natalia Baran,Natalie W. Fowlkes,Ken Chen,Luis Muniz-Feliciano,Richard E. Champlin,Yago Nieto,Joachim Koch,Martin Treder,Wolfgang Fischer,Oswaldo Keith Okamoto,Elizabeth J. Shpall,Todd A. Fehniger,Katayoun Rezvani +43 more
TL;DR: In this article, the tetravalent bispecific antibody AFM13 and IL12/15/18 pre-activation of blood and cord-derived NK cells was investigated in vitro and in vivo.
Journal ArticleDOI
Challenges and opportunities in primary CNS lymphoma: A systematic review.
Mariana Nassif Kerbauy,Fabio Y. Moraes,Fabio Y. Moraes,Benjamin H. Lok,Jennifer Ma,Lucila Nassif Kerbauy,Daniel E. Spratt,Fabio P.S. Santos,Guilherme Fleury Perini,Alejandro Berlin,Caroline Chung,Nelson Hamerschlak,Joachim Yahalom +12 more
TL;DR: WBRT for consolidation is a well-studied modality; however emerging options to selected population such as HDC-ASCT, dose-reduced WBRT or chemotherapy alone are associated with similar survival outcome and less neurotoxicity in selected series.