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Journal ArticleDOI

Quantum dots versus organic dyes as fluorescent labels

TLDR
This work compares and evaluates the differences in physicochemical properties of common fluorescent labels, focusing on traditional organic dyes and QDs, to provide a better understanding of the advantages and limitations of both classes of chromophores.
Abstract
Suitable labels are at the core of Luminescence and fluorescence imaging and sensing. One of the most exciting, yet also controversial, advances in label technology is the emerging development of quantum dots (QDs)--inorganic nanocrystals with unique optical and chemical properties but complicated surface chemistry--as in vitro and in vivo fluorophores. Here we compare and evaluate the differences in physicochemical properties of common fluorescent labels, focusing on traditional organic dyes and QDs. Our aim is to provide a better understanding of the advantages and limitations of both classes of chromophores, to facilitate label choice and to address future challenges in the rational design and manipulation of QD labels.

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Citations
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Journal ArticleDOI

Emergence of colloidal quantum-dot light-emitting technologies

TL;DR: In this paper, the authors summarized the key advantages of using quantum dots as luminophores in light-emitting devices (LEDs) and outlined the operating mechanisms of four types of QD-LEDs.
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Near-infrared fluorophores for biomedical imaging

TL;DR: This Review covers recent progress on near-infrared fluorescence imaging for preclinical animal studies and clinical diagnostics and interventions.
Journal ArticleDOI

Luminescent probes and sensors for temperature.

TL;DR: This Review article focuses on all kinds of luminescent probes and sensors for measurement of T, and summarizes the recent progress in their design and application formats.
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A review of NIR dyes in cancer targeting and imaging.

TL;DR: It is believed these newly developed multifunctional NIR dyes will broaden current concept of tumor targeted imaging and hold promise to make an important contribution to the diagnosis and therapeutics for the treatment of cancer.
References
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Book

Principles of fluorescence spectroscopy

TL;DR: This book describes the fundamental aspects of fluorescence, the biochemical applications of this methodology, and the instrumentation used in fluorescence spectroscopy.
Journal ArticleDOI

Semiconductor Clusters, Nanocrystals, and Quantum Dots

TL;DR: In this article, the authors focus on the properties of quantum dots and their ability to join the dots into complex assemblies creates many opportunities for scientific discovery, such as the ability of joining the dots to complex assemblies.
Journal ArticleDOI

Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection

TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal ArticleDOI

Quantum dot bioconjugates for imaging, labelling and sensing

TL;DR: This review looks at current methods for preparing QD bioconjugates as well as presenting an overview of applications, and concludes that the potential of QDs in biology has just begun to be realized and new avenues will arise as the ability to manipulate these materials improves.
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