Roland W. J. Hangelbroek

TL;DR: It is indicated that acute endurance exercise elicits pronounced changes in gene expression in non-exercising muscle, which is likely mediated by changes in circulating factors such as free fatty acids.

TL;DR: Almost all athletes had used nutritional supplements at some time during their athletic career and receiving dietary counseling seemed to result in better-informed choices with respect to the use of nutritional supplements related to performance, recovery, and health.

TL;DR: Only modest correlations between muscle and plasma metabolite levels are observed, which pleads against the use of plasma metabolites as a direct read-out of muscle metabolism and stresses the need for direct assessment of metabolites in muscle tissue biopsies.

TL;DR: Differences in the skeletal muscle transcriptome between healthy young and older subjects and (pre‐)frail older adults are examined and the effect of resistance‐type exercise training on the muscle transcriptsome is examined.

TL;DR: Creatine supplementation prior to and during leg immobilization does not prevent or attenuate the loss of muscle mass or strength during short-term muscle disuse.