R
Ronald P. Brown
Researcher at Center for Devices and Radiological Health
Publications - 24
Citations - 1215
Ronald P. Brown is an academic researcher from Center for Devices and Radiological Health. The author has contributed to research in topics: Kidney & Acute kidney injury. The author has an hindex of 14, co-authored 24 publications receiving 1040 citations.
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Journal ArticleDOI
Comparison of Kidney Injury Molecule-1 and Other Nephrotoxicity Biomarkers in Urine and Kidney Following Acute Exposure to Gentamicin, Mercury, and Chromium
Yuzhao Zhou,Vishal S. Vaidya,Ronald P. Brown,Jun Zhang,Barry A. Rosenzweig,Karol L. Thompson,Terry J. Miller,Joseph V. Bonventre,Peter L. Goering +8 more
TL;DR: Urinary Kim- 1 and kidney Kim-1/Havcr1 expression appear to be sensitive and tissue-specific biomarkers that will improve detection of early acute kidney injury following exposure to nephrotoxic chemicals and drugs.
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Silver nanoparticles: Significance of physicochemical properties and assay interference on the interpretation of in vitro cytotoxicity studies.
Kausar Begam Riaz Ahmed,Amber M. Nagy,Ronald P. Brown,Qin Zhang,Subhas G. Malghan,Peter L. Goering +5 more
TL;DR: The goal of this review is to summarize the impact of physical-chemical parameters, including size, shape, surface chemistry and aggregate formation on the in vitro cytotoxic effects of AgNPs; and explore the nature ofAgNPs interference in in vivo cytotoxicity assays.
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Expression, circulation, and excretion profile of microRNA-21, -155, and -18a following acute kidney injury.
Janani Saikumar,Dana Hoffmann,Tae-Min Kim,Victoria Ramirez Gonzalez,Qin Zhang,Peter L. Goering,Ronald P. Brown,Vanesa Bijol,Peter J. Park,Sushrut S. Waikar,Vishal S. Vaidya,Vishal S. Vaidya +11 more
TL;DR: Results suggest that miRNA-21 and -155 could potentially serve as translational biomarkers for detection of AKI and may play a critical role in the pathogenesis of kidney injury and tissue repair process.
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Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague-Dawley rats.
TL;DR: Results show that concentrations of aglycone BPA in fetal tissues are similar to those in other maternal and neonatal tissues and that maternal Phase II metabolism, especially following oral administration, and fetal age are critical in reducing exposures to the fetus.
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Clinically relevant concentrations of di (2-ethylhexyl) phthalate (DEHP) uncouple cardiac syncytium.
TL;DR: The data indicate that DEHP, in clinically relevant concentrations, can impair the electrical and mechanical behavior of a cardiac cell network, and applicability of these findings to human patients remains to be established.