Rongrong Zhang

TL;DR: It is demonstrated that the Wnt/β-catenin signaling pathway is an upstream activator of BMP2 expression in osteoblasts, providing novel insights into the nature of functional cross talk integrating the BMP and Wnt /β- catenin pathways in osteoblast differentiation and maintenance of skeletal homeostasis.

TL;DR: The results demonstrate that the anabolic function of PTH signaling in bone is mediated, at least in part, by CREB transactivation of BMP2 expression in osteoblasts.

TL;DR: The observed functional redundancy of type II BMP receptors in osteoblasts is novel information about the BMP signaling pathway essential for initiating osteoblast differentiation.

TL;DR: The results suggest that stathmin, which alters microtubule dynamics, plays an essential role in maintenance of postnatal bone mass by regulating both osteoblast and osteoclast functions in bone.

TL;DR: It is demonstrated that kaempferol could inhibit HSC activation, at least in part, via miR-26b-5p-mediated Jag1 axis and Notch pathway and may serve as a promising drug in the application of treating liver fibrosis.