R
Ronit Shtrichman
Researcher at Technion – Israel Institute of Technology
Publications - 21
Citations - 1458
Ronit Shtrichman is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 14, co-authored 20 publications receiving 1330 citations. Previous affiliations of Ronit Shtrichman include Rappaport Faculty of Medicine.
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Journal ArticleDOI
Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulation
Atara Novak,Lili Barad,Naama Zeevi-Levin,Revital Shick,Ronit Shtrichman,Avraham Lorber,Avraham Lorber,Joseph Itskovitz-Eldor,Joseph Itskovitz-Eldor,Ofer Binah +9 more
TL;DR: The results demonstrate that the patient‐specific mutated cardiomyocytes can be used to study the electrophysiological mechanisms underlying CPVT, and investigate catecholamine‐induced arrhythmias in the CASQ2 mutated cells.
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GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data
Shani Ben-Ari Fuchs,Iris Lieder,Gil Stelzer,Yaron Mazor,Ella Buzhor,Sergey Kaplan,Yoel Bogoch,Inbar Plaschkes,Alina Shitrit,Noa Rappaport,Asher Kohn,Ron Edgar,Liraz Shenhav,Marilyn Safran,Doron Lancet,Yaron Guan-Golan,David Warshawsky,Ronit Shtrichman +17 more
TL;DR: This study reports on GeneAnalytics™ (geneanalytics.org), a comprehensive and easy-to-apply gene set analysis tool for rapid contextualization of expression patterns and functional signatures embedded in the postgenomics Big Data domains, such as Next Generation Sequencing, RNAseq, and microarray experiments.
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Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A
TL;DR: The results suggest that E4orf4 is a potentially useful tool for cancer gene therapy and indicates that expression of oncogenes in primary cell cultures sensitizes these cells to induction of apoptosis by E 4orf4.
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Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells
Igal Germanguz,Oshra Sedan,Oshra Sedan,Naama Zeevi-Levin,Naama Zeevi-Levin,Ronit Shtrichman,Ronit Shtrichman,Efrat Barak,Efrat Barak,Anna Ziskind,Anna Ziskind,Sivan Eliyahu,Sivan Eliyahu,Gideon Meiry,Gideon Meiry,Michal Amit,Michal Amit,Joseph Itskovitz-Eldor,Joseph Itskovitz-Eldor,Ofer Binah,Ofer Binah +20 more
TL;DR: This study demonstrates that in the cardiomyocytes clones differentiated from HFF‐derived iPS, the functional properties related to excitation–contraction coupling, resemble in part those of adult card iomyocytes.
Journal ArticleDOI
Adenovirus Type 5 E4 Open Reading Frame 4 Protein Induces Apoptosis in Transformed Cells
TL;DR: It is suggested that E4orf4 antagonizes continuous signals to proliferate, like those given by E1A or v-Ras, and that the conflicting signals lead to the induction of cell death.