Anna Ziskind

TL;DR: The isolation of human embryonic stem (hES) cells introduced a new prospect for obtaining a sufficient number of β cells for transplantation for type I diabetes mellitus.

TL;DR: Undifferentiated hESCs and hEBs are not directed to form new myocardium after transplantation into normal or infarcted heart and may create teratoma, but hESC-derived cardiomyocyte transplantation can attenuate post-MI scar thinning and left ventricular dysfunction.

TL;DR: It is reported that human embryoid bodies can be generated directly from hESC suspensions within three‐dimensional (3D) porous alginate scaffolds and it is concluded that differentiation of hEBs can be induced and directed by physical constraints in addition to chemical cues.

TL;DR: HES cells can provide useful models to study early differentiation and development of blood vessels and the 2D differentiation model facilitates both the production of vascular lineage cells from HES cells for various potential therapeutic applications and also provides a model for studying the mechanisms involved in early human embryonic blood vessel development.

TL;DR: This study demonstrates that in the cardiomyocytes clones differentiated from HFF‐derived iPS, the functional properties related to excitation–contraction coupling, resemble in part those of adult card iomyocytes.