R
Rosa M. Alonso
Researcher at University of the Basque Country
Publications - 160
Citations - 3222
Rosa M. Alonso is an academic researcher from University of the Basque Country. The author has contributed to research in topics: High-performance liquid chromatography & Detection limit. The author has an hindex of 30, co-authored 150 publications receiving 2940 citations. Previous affiliations of Rosa M. Alonso include University of Coimbra & University of the Balearic Islands.
Papers
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Bioanalytical chromatographic method validation according to current regulations, with a special focus on the non-well defined parameters limit of quantification, robustness and matrix effect.
Oskar González,María Encarnación Blanco,Gorka Iriarte,L. Bartolomé,M.I. Maguregui,Rosa M. Alonso +5 more
TL;DR: The overall validation process including common validation parameters (selectivity, linearity range, precision, accuracy, stability…) will be reviewed, the most controversial parameters (limit of quantification, robustness and matrix effect) will be carefully studied and the definitions and methodology proposed by the different regulatory bodies will be compared.
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Fast screening method for the determination of angiotensin II receptor antagonists in human plasma by high-performance liquid chromatography with fluorimetric detection.
TL;DR: A selective, accurate and precise high-performance liquid chromatographic assay coupled to fluorescence detection was developed for the detection of some angiotensin II receptor antagonists (ARA II) and has been successfully applied to plasma samples obtained from hypertensive patients.
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pKa determination of angiotensin II receptor antagonists (ARA II) by spectrofluorimetry
TL;DR: The acid-base equilibrium constants of a new family of antihypertensive drugs, the angiotensin II receptor antagonists (ARA II), Losartan, Irbesartan (Valsartan), ValsartAn, Candesartan cilexetil, its metabolite Candeartan M1 and Telmisartan were determined by spectrofluorimetry.
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Analytical methods for dating modern writing instrument inks on paper
TL;DR: The study, done chronologically, shows the advances experienced in the ink dating field in the last decades.
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Experimental design methodologies to optimise the spectrofluorimetric determination of Losartan and Valsartan in human urine.
TL;DR: A spectrofluorimetric method has been developed for the determination of two angiotensin II receptor antagonists (ARA II): Losartan and Valsartan using a fractional factorial design and a central composite design.