R
Rosa M. Villalba
Researcher at Yerkes National Primate Research Center
Publications - 46
Citations - 2201
Rosa M. Villalba is an academic researcher from Yerkes National Primate Research Center. The author has contributed to research in topics: Striatum & Dendritic spine. The author has an hindex of 25, co-authored 46 publications receiving 1948 citations. Previous affiliations of Rosa M. Villalba include Spanish National Research Council & Wright State University.
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Journal ArticleDOI
Vesicular glutamate transporters in the spinal cord, with special reference to sensory primary afferent synapses
TL;DR: Results indicate a diversity of VGLUT isoform combinations expressed in different spinal primary afferents, suggesting a preferential intrinsic origin.
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The thalamostriatal system in normal and diseased states
Yoland Smith,Adriana Galván,Tommas J. Ellender,Natalie M. Doig,Rosa M. Villalba,Icnelia Huerta-Ocampo,Thomas Wichmann,J. P. Bolam +7 more
TL;DR: Optogenetic methods and evidence largely gathered from thalamic recordings in awake monkeys strongly suggests that the thalamostriatal system from the CM/Pf is involved in regulating alertness and switching behaviors, and there is evidence that the caudal intralaminar nuclei and their axonal projections to the striatum partly degenerate in PD.
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Striatal and extrastriatal dopamine in the basal ganglia: an overview of its anatomical organization in normal and Parkinsonian brains.
Yoland Smith,Rosa M. Villalba +1 more
TL;DR: The importance and specificity of dopamine in regulating morphological changes in striatal projection neurons provides further evidence for the complex and multifarious mechanisms through which dopamine mediates its functional effects in the basal ganglia.
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Dopaminergic denervation and spine loss in the striatum of MPTP-treated monkeys
TL;DR: The data demonstrate that striatal spine loss in MPTP-treated monkeys is an early pathological event of parkinsonism, tightly correlated with the degree of nigrostriatal dopamine denervation that likely affects both direct and indirect striatofugal pathways.
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Differential distribution of metabotropic glutamate receptors 1a, 1b, and 5 in the rat spinal cord.
Francisco J. Alvarez,Rosa M. Villalba,Patrick A. Carr,Patrick A. Carr,Pedro Grandes,Paula M. Somohano +5 more
TL;DR: Type I mGluR immunoreactivity was found mostly at extrasynaptic sites on the plasma membrane, but it was also found perisynaptically, in the body of the postsynaptic regions or in relation to intracytoplasmic structures.