Rosangela Tozzoli

TL;DR: Using a consistent schema for nomenclature of the Stx toxins and stx genes by phylogenetic sequence-based relatedness of the holotoxin proteins, a typing approach should obviate the need to bioassay each newly described toxin and that predicts important biological characteristics.

TL;DR: Simple diagnostic screening tools to detect the outbreak strain in clinical specimens and a novel real-time PCR for its detection in foods are described.

TL;DR: It is demonstrated that in many EHEC non-O157 strains and EPEC strains belonging to eight serogroups, PAI O122 and the LEE are physically linked to form a cointegrated structure that can be considered a mosaic PAI that could have been acquired originally by AEEC.

TL;DR: Patients with STEC-HUS had great benefit from early volume expansion and it is speculated that early and generous fluid infusions can reduce thrombus formation and ischemic organ damage, thus having positive effects on both short- and long-term disease outcomes.

TL;DR: The results suggest that the stx2-phages used may not have specificity for E. coli adapted to the intestinal environment, at least in the conditions used, and could only observe transient lysogens suggesting that the event of stable stx1-phage acquisition occurs rarely.