S
Søren Persson
Researcher at Statens Serum Institut
Publications - 23
Citations - 2607
Søren Persson is an academic researcher from Statens Serum Institut. The author has contributed to research in topics: Clostridium difficile & Campylobacter jejuni. The author has an hindex of 15, co-authored 22 publications receiving 2216 citations.
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Journal ArticleDOI
Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature
Flemming Scheutz,Louise D. Teel,Lothar Beutin,Denis Pierard,Glenn Buvens,Helge Karch,Alexander Mellmann,Alfredo Caprioli,Rosangela Tozzoli,Stefano Morabito,Nancy A. Strockbine,Angela R. Melton-Celsa,Maria A. Sanchez,Søren Persson,Alison D. O'Brien +14 more
TL;DR: Using a consistent schema for nomenclature of the Stx toxins and stx genes by phylogenetic sequence-based relatedness of the holotoxin proteins, a typing approach should obviate the need to bioassay each newly described toxin and that predicts important biological characteristics.
Journal ArticleDOI
Towards standards for human fecal sample processing in metagenomic studies
Paul I. Costea,Georg Zeller,Shinichi Sunagawa,Eric Pelletier,Eric Pelletier,Adriana Alberti,Florence Levenez,Melanie Tramontano,Marja Driessen,Rajna Hercog,Ferris Elias Jung,Jens Roat Kultima,Matthew R. Hayward,Luis Pedro Coelho,Emma Allen-Vercoe,Laurie Bertrand,Michael Blaut,Jillian R.M. Brown,Thomas Carton,Stéphanie Cools-Portier,Michelle C. Daigneault,Muriel Derrien,Anne Druesne,Willem M. de Vos,Willem M. de Vos,B. Brett Finlay,Harry J. Flint,Francisco Guarner,Masahira Hattori,Masahira Hattori,Hans G.H.J. Heilig,Ruth Ann Luna,Johan E. T. van Hylckama Vlieg,Jana Junick,Ingeborg Klymiuk,Philippe Langella,Volker Mai,Chaysavanh Manichanh,Jennifer C. Martin,Clémentine Mery,Hidetoshi Morita,Paul W. O'Toole,Céline Orvain,Kiran Raosaheb Patil,John Penders,Søren Persson,Nicolas Pons,Milena Popova,Anne Salonen,Delphine M. Saulnier,Karen P. Scott,Bhagirath Singh,Kathleen Slezak,Patrick Veiga,James Versalovic,Liping Zhao,Erwin G. Zoetendal,S. Dusko Ehrlich,S. Dusko Ehrlich,Joël Doré,Peer Bork +60 more
TL;DR: A standardized DNA extraction method for human fecal samples is recommended, for which transferability across labs was established and which was further benchmarked using a mock community of known composition to improve comparability of human gut microbiome studies and facilitate meta-analyses.
Journal ArticleDOI
Subtyping Method for Escherichia coli Shiga Toxin (Verocytotoxin) 2 Variants and Correlations to Clinical Manifestations
TL;DR: Shiga toxin 2 from Shiga toxin-producing Escherichia coli (STEC) was subtyped by a method involving partial sequencing of the stxAB2 operon and all 20 cases of hemolytic-uremic syndrome were associated with subtype Stx2.
Journal ArticleDOI
New multiplex PCR method for the detection of Clostridium difficile toxin A (tcdA) and toxin B (tcdB) and the binary toxin (cdtA/cdtB) genes applied to a Danish strain collection
TL;DR: The 5-plex PCR method offers a one-step, rapid and specific screening method for C. difficile toxin genes and together with deletion studies in tcdA and tcdC, may allow an evaluation of the pathogenic potential of C. Difficile.
Journal ArticleDOI
Genomic characterization of enteroaggregative Escherichia coli from children in Mali.
Nadia Boisen,Flemming Scheutz,David A. Rasko,Julia C. Redman,Søren Persson,Jakub K. Simon,Karen L. Kotloff,Myron M. Levine,Samba O. Sow,Boubou Tamboura,Aliou Toure,Dramane Malle,Sandra Panchalingam,Karen A. Krogfelt,James P. Nataro +14 more
TL;DR: The data suggest that only a subset of EAEC strains are pathogenic in Mali and suggest that sepA may serve as a valuable marker for the most virulent isolates, as well as suggesting combinations of factors most strongly associated with illness.