R
Roy C. P. Kerckhoffs
Researcher at University of California, San Diego
Publications - 41
Citations - 1766
Roy C. P. Kerckhoffs is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Heart failure & Cardiac resynchronization therapy. The author has an hindex of 20, co-authored 41 publications receiving 1638 citations. Previous affiliations of Roy C. P. Kerckhoffs include University of California, Berkeley & Eindhoven University of Technology.
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Journal ArticleDOI
Coupling of a 3D Finite Element Model of Cardiac Ventricular Mechanics to Lumped Systems Models of the Systemic and Pulmonic Circulation
Roy C. P. Kerckhoffs,Maxwell Lewis Neal,Quan Gu,James B. Bassingthwaighte,Jeffrey H. Omens,Andrew D. McCulloch +5 more
TL;DR: A novel, robust method to couple finite element models of cardiac mechanics to systems models of the circulation, independent of cardiac phase is presented, encompassing levels from cell to system.
Journal ArticleDOI
Homogeneity of cardiac contraction despite physiological asynchrony of depolarization: a model study.
Roy C. P. Kerckhoffs,Peter H. M. Bovendeerd,J. C. S. Kotte,Frits W. Prinzen,K Karel Smits,Theo Arts +5 more
TL;DR: The present finding may indicate that electromechanical delay times are heterogeneously distributed, such that a contraction in a normal heart is more synchronous than depolarization.
Journal ArticleDOI
Patient-specific models of cardiac biomechanics
Adarsh Krishnamurthy,Christopher T. Villongco,Joyce Chuang,Lawrence R. Frank,Vishal Nigam,Ernest Belezzuoli,Paul Stark,David E. Krummen,Sanjiv M. Narayan,Jeffrey H. Omens,Andrew D. McCulloch,Roy C. P. Kerckhoffs +11 more
TL;DR: New methods for creating three-dimensional patient-specific models of ventricular biomechanics in the failing heart showed good agreement with measured echocardiographic and global functional parameters such as ejection fraction and peak cavity pressures.
Journal ArticleDOI
Current progress in patient-specific modeling
TL;DR: A survey of recent advancements in the emerging field of patient-specific modeling (PSM) suggests that with further testing and research, PSM-derived technologies will eventually become valuable, versatile clinical tools.
Journal ArticleDOI
Patient-specific modeling of dyssynchronous heart failure: a case study.
Jazmin Aguado-Sierra,Adarsh Krishnamurthy,Christopher T. Villongco,Joyce Chuang,Elliot J. Howard,Matthew J. Gonzales,Jeffrey H. Omens,David E. Krummen,David E. Krummen,Sanjiv M. Narayan,Sanjiv M. Narayan,Roy C. P. Kerckhoffs,Andrew D. McCulloch +12 more
TL;DR: Some of the remaining challenges in developing reliable patient-specific models of cardiac electromechanical activity are discussed, and some of the main areas for focusing future research efforts are identified.