Rudolf Likar

TL;DR: The criteria for selecting analgesics for pain treatment in the elderly include, but are not limited to, overall efficacy, overall side‐effect profile, onset of action, drug interactions, abuse potential, and practical issues, such as cost and availability of the drug, as well as the severity and type of pain.

TL;DR: Buprenorphine exhibits a pronounced antihyperalgesic effect that might indicate potential advantages in the treatment of neuropathic pain, and its favorable safety profile and proven efficacy in severe pain and favorable tolerability mean that it can be considered a safe and effective option for treating chronic cancer and noncancer pain.

TL;DR: Despite the increasing clinical use of transder-mal buprenorphine, questions have persisted about the possibility of a ceiling effect for analgesia, its combination as discussed by the authors, and its combination.

TL;DR: To evaluate the effectiveness of tapentadol prolonged release (PR) vs. oxycodone/naloxone PR in non–opioid‐pretreated patients with severe chronic low back pain with a neuropathic pain component, a comparison study is conducted.

TL;DR: The retrospective data analysis revealed that STS effectively provided pain relief in patients suffering from refractory focal chronic noncancer pain and that STs is an alternative treatment option.