R
Rudy Bonfilio
Researcher at Universidade Federal de Alfenas
Publications - 42
Citations - 590
Rudy Bonfilio is an academic researcher from Universidade Federal de Alfenas. The author has contributed to research in topics: Dissolution testing & Solubility. The author has an hindex of 15, co-authored 40 publications receiving 447 citations. Previous affiliations of Rudy Bonfilio include Universidade Federal de Mato Grosso & Sao Paulo State University.
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Journal ArticleDOI
Development and characterization of nanostructured lipid carrier-based gels for the transdermal delivery of donepezil.
I.T. Mendes,André Luís Morais Ruela,Flávia Chiva Carvalho,Jennifer Tavares Jacon Freitas,Rudy Bonfilio,Gislaine Ribeiro Pereira +5 more
TL;DR: Results indicated that drug skin permeation from DPB-NLC gel was increased, not only by the enhancing effect of their components, but the lipid nanocarriers also presented an additional enhancing effect to increase drug flux across the skin.
Journal ArticleDOI
Analysis of polymorphic contamination in meloxicam raw materials and its effects on the physicochemical quality of drug product
Jennifer Tavares Jacon Freitas,Olimpia Maria Martins Santos Viana,Rudy Bonfilio,Antonio C. Doriguetto,Magali Benjamim Araújo +4 more
TL;DR: The results illustrate the importance of the polymorphic characterization of meloxicam APIs and formulated tablets in order to avoid potential quality and efficacy problems of drug products.
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Mucoadhesive nanostructured lipid carriers as a cannabidiol nasal delivery system for the treatment of neuropathic pain.
Ananda Pulini Matarazzo,Lívia Maria Silvestre Elisei,Flávia Chiva Carvalho,Rudy Bonfilio,André Luís Morais Ruela,Giovane Galdino,Gislaine Ribeiro Pereira +6 more
TL;DR: In this paper, the authors developed nanostructured lipid carriers (NLCs) for the nasal administration of cannabidiol (CBD) to treat several pathologies, including those in which pain is prevalent.
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Analytical Validation of Quantitative High-Performance Liquid Chromatographic Methods in Pharmaceutical Analysis: A Practical Approach
Rudy Bonfilio,Edith Cristina Laignier Cazedey,Magali Benjamim Araújo,Hérida Regina Nunes Salgado +3 more
TL;DR: Aiming to assist in the planning of validation methods, relevant approaches of various parameters in quantitative high-performance liquid chromatographic methods and validation fields in pharmaceutical analysis are discussed.
Journal ArticleDOI
Multivariate optimization and validation of an analytical methodology by RP-HPLC for the determination of losartan potassium in capsules
Rudy Bonfilio,César Ricardo Teixeira Tarley,César Ricardo Teixeira Tarley,Gislaine Ribeiro Pereira,Hérida Regina Nunes Salgado,Magali Benjamim Araújo +5 more
TL;DR: The optimization and validation of an analytical methodology for the determination of losartan potassium in capsules by HPLC using 2(5-1) fractional factorial and Doehlert designs is described, showing accuracy, precision, selectivity, robustness and linearity.