Ruei-Zeng Lin

TL;DR: The suitability of a photopolymerizable gelatin methacrylate (GelMA) hydrogel to support human progenitor cell‐based formation of vascular networks is demonstrated and it is shown that implantation of cell‐laden GelMA hydrogels into immunodeficient mice results in a rapid formation of functional anastomoses between the bioengineered human vascular network and the mouse vasculature.

TL;DR: Genetic fate-mapping approaches in mice indicate that epicardium modulates the cardiac injury response by conditioning the subepicardial environment, potentially offering a new therapeutic strategy for cardiac protection.

TL;DR: In vitro reconstruction of the heterogeneous lobule-mimetic radial pattern with good cell viability after cell patterning is demonstrated and reported by this cell-lab chip.

TL;DR: It is shown that β1-integrin and E-cadherin activity with specific blocking antibodies, ion chelators, and RGD-sequence-containing peptides mediate the formation of spheroids through the establishment of complex cell-cell and cell-extracellular matrix (ECM) interactions.

TL;DR: A lobule-mimetic cell-patterning technique for on-chip reconstruction of centimetre-scale liver tissue of heterogeneous hepatic and endothelial cells via an enhanced field-induced dielectrophoresis (DEP) trap is demonstrated and reported.