Rui Chen

TL;DR: UFPs play a major role in adverse impacts on human health and require further investigations in future toxicological research of air pollution and the knowledge of nanotoxicology contributes to the understanding of toxicity mechanisms of airborne UFPs in air pollution.

TL;DR: PM2.5 exposure reversibly elevated heart rate and blood pressure, induced cardiac systolic dysfunction of older mice, and reversibly induced fibrosis in juvenile and older mice is found.

TL;DR: In this article, the authors investigated the toxic effects of pristine polystyrene (PS) M/NPLs for 28 days, leading to the decreased expression of tight junction proteins.

TL;DR: An intelligent analytical strategy for safety assessment of NMs is proposed that focuses on toxicity assessment using an in vitro cell model, and the most commonly used techniques and analytical methods are discussed, including computational toxicology methods in dosimetry assessment, high-throughput screening for toxicity testing with high efficiency, and omics-based toxicology assessment methods.

TL;DR: Developed empirical equations provided a tool to quantify inhaled nanoparticle dose in human and rat nasal olfactory regions, which lay the ground work for comprehensive interspecies correlation between the two species, in long-term and low-dose inhalation exposure scenarios.