Ruirui Qi

TL;DR: This review summarizes the current knowledge about pathogenesis and pathophysiology, prediction, evaluation, and countermeasures of MS, and indicates that the sensory conflict hypothesis is the most widely accepted theory for MS.

TL;DR: It is reported that IO induced similar inflammatory responses in human primary hepatocytes and Thp-1-derived macrophages and hepatocyte-specific overexpression of miR-122 rescued IO-mediated hepatic inflammation.

TL;DR: The results suggested that the alteration of OXA expression might contribute to locomotor abnormalities after acute vestibular lesion and the orexin receptors might be the potential therapeutic targets for Vestibular disorders.

TL;DR: A dual-luciferase reporter assay is used to prove that miR-122 regulates CCL2 expression through direct binding to its complementary sequence in the CCL1 mRNA 3’UTR, and propose the roles of miR -122/CCL2 in IO-induced hepatic inflammation.

TL;DR: The results suggested that the sex and age differences in motion sickness may not correlate with stress hormone responses and habituation, and the age-dependent decline inmotion sickness susceptibility might be mainly attributed to the neuronal activity changes in vestibulo-autonomic pathways contributing to homeostasis regulation during motion sickness.